An open-label non-randomized prospective pilot study of the efficacy of Q-switched Nd-YAG laser in management of facial lichen planus pigmentosus

Abstract

Lichen planus pigmentosus (LPP) is a cosmetically disfiguring condition. Many treatment options are available which are effective in halting the progression of the disease. The treatment of persistent pigmentation is still a challenge. We describe the use of Q-switched Nd-YAG laser in 13 patients with stable LPP using a standard protocol. Most of our patients showed complete to near-complete resolution of pigment without much complications.

Effect of Q‐switched Nd‐YAG laser on the clinical, pigmentary, and immunological markers in patients with lichen planus pigmentosus: A pilot study

“…However, there is paucity of information on pigmentary lasers in treating LPP in Indian skin types. A recent study with thirteen patients of LPP used standard protocol of QS Nd‐YAG laser with 5 mm spot size, fluence 3–4.6 J/cm 2 and 5‐Hz repetition rate and showed satisfactory clinical response after five to six sessions (Shah, Aurangabadkar, & Nikam, ). Further studies are warranted to provide definite data not only regarding the efficacy of laser treatment, but also the laser parameters, number, and frequency of sessions required for the successful treatment of LPP in Indian patients.…”

Acquired Dermal Macular Hyperpigmentation

“…A similar study by Shah et al . [ 37 ] showed a maximal improvement of 38% in LPP patients. The combination of topical tacrolimus 0.1%, hydroxychloroquine 200 mg twice a day and Vitamin C iontophoresis for 6 months resulted in the stabilization of the hyperpigmentation.…”

Ashy dermatosis: a review

“…Topical tacrolimus for 8 weeks renders moderate treatment success in lichen planus pigmentosus [48]. Qswitched Nd-YAG laser in combination with topical tacrolimus is also effective in treating stable lichen planus pigmentosus [49].…”