An online pH detection system based on a microfluidic chip

Lu, Yu; Feng, Qianru; Zhang, Ruohu; Lu, Hui; Su, Jing‐Ting; Cui, Yiping; Zhu, Li

doi:10.1016/j.aca.2020.01.063

Cited by 14 publications

(6 citation statements)

References 30 publications

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“…The capabilities of this electrocatalytic sensor were examined for synthetic wine fermentation process, with promising results for in situ monitoring. Lu et al [73] developed a pH detection device based on a microfluidic chip that can measure pH levels in extreme acidic and alkaline situations in real time. A pH sensor membrane, as well as a light source and photodiode, were used along with a microfluidic chamber to create the sensing chip.…”

Section: Fermentationmentioning

confidence: 99%

Microfluidics and the Spirits Industry: A Review

Mondal,

Williams

2023

JDS

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There is and will always be the need to provide authentic and safe alcoholic beverages. To achieve this goal, researchers are constantly looking for innovative and practical approaches to analyze their samples and control their quality. Quality control can be challenging in the spirits industry due to their production (mashing, fermenting, distilling, aging, packaging) and their complex chemical composition. To assess the quality and safety of alcoholic beverages, a variety of analytical procedures have been developed and are currently in use. Although these laboratory-based approaches offer a high level of sensitivity, they can be both time-consuming and costly. Therefore, it is an ongoing need to advance simpler, faster, more precise, field-deployable, and more sensitive instruments to identify chemicals and abnormalities in alcoholic beverages. We believe many needs can be addressed using microfluidic technologies, sometimes referred to as lab-on-a-chip devices. In this review, we will discuss recent significant advancements in microfluidics for the assessment of alcoholic beverage products. The analysis and viewpoints presented in this study are intended to stimulate continued development of microfluidic devices in the spirits sector and other food safety testing and monitoring fields, benefiting human health and overall well-being.

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Section: Fermentationmentioning

confidence: 99%

Microfluidics and the Spirits Industry: A Review

Mondal,

Williams

2023

JDS

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“…[ 122–124 ] The potentiometric biosensors are widely used for the biologically fluid analysis of pH and ions such as Na + , K + , Ca 2+ , and Cl – . [ 85,125,126 ] For transdermal detection, Miller et al. [ 97 ] utilized the hollow MNs to draw ISF and ion selective electrodes to measure the concentration of K + within a microfluidic chip.…”

Section: Microneedles (Mns) For Transdermal Diagnosismentioning

confidence: 99%

“…[122][123][124] The potentiometric biosensors are widely used for the biologically fluid analysis of pH and ions such as Na + , K + , Ca 2+ , and Cl -. [85,125,126] For transdermal detection, Miller et al [97] utilized the hollow MNs to draw ISF and ion selective electrodes to measure the concentration of K + within a microfluidic chip. Whereafter, Gowers et al [54] reported a MNs-based electrochemical biosensor for monitoring 𝛽-lactam antibiotic by open circuit potential (OCP) method (Figure 2a).…”

Section: Electrochemistrymentioning

confidence: 99%

Recent Progress in Microneedles‐Mediated Diagnosis, Therapy, and Theranostic Systems

Yang

Gong

et al. 2022

Adv Healthcare Materials

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Theranostic system combined diagnostic and therapeutic modalities is critical for the real-time monitoring of disease-related biomarkers and personalized therapy. Microneedles, as a multifunctional platform, are promising for transdermal diagnostics and drug delivery. They have shown attractive properties including painless skin penetration, easy self-administration, prominent therapeutic effects, and good biosafety. Herein, an overview of the microneedles-based diagnosis, therapies, and theranostic systems is given. Four microneedles-based detection methods are concluded based on the sensing mechanism: i) electrochemistry, ii) fluorometric, iii) colorimetric, and iv) Raman methods. Additionally, robust microneedles are suitable for implantable drug delivery. Microneedles-assisted transdermal drug delivery can be primarily classified as passive, active, and responsive drug release, based on the release mechanisms. Microneedles-assisted oral and implantable drug delivery mechanisms are also presented in this review. Furthermore, the key frontier developments in microneedles-mediated theranostic systems as the major selling points are emphasized in this review. These systems are classified into open-loop and closed-loop theranostic systems based on the indirectness and directness of feedback between the transdermal diagnosis and therapy, respectively. Finally, conclusions and future perspectives for next-generation microneedles-mediated theranostic systems are also discussed. Taken together, microneedle-based systems are promising as the new avenue for diagnosis, therapy, and disease-specific closed-loop theranostic applications.

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“…Variation of pH in the environment may affect people’s living condition. Therefore, it is vital to investigate the spectral properties of compounds in different acids and bases. − …”

Section: Response To Phmentioning

confidence: 99%

Schiff Base Aggregation-Induced Emission Luminogens for Sensing Applications: A Review

et al. 2022

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Fluorescence sensing can not only identify a target substrate qualitatively but also achieve the purpose of quantitative detection through the change of the fluorescence signal. It has the advantages of immense sensitivity, rapid response, and excellent selectivity. The proposed aggregation-induced emission (AIE) concept solves the problem of the fluorescence of traditional fluorescent molecules becoming weak or quenched in high concentration or aggregated state conditions. Schiff base fluorescent probes have the advantages of simple synthesis, low toxicity, and easy design. They are often used for the detection of various substances. In this review we cover late developments in Schiff base compounds with AIE characteristics working as fluorescence sensors.

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An online pH detection system based on a microfluidic chip

Cited by 14 publications

References 30 publications

Microfluidics and the Spirits Industry: A Review

Microfluidics and the Spirits Industry: A Review

Recent Progress in Microneedles‐Mediated Diagnosis, Therapy, and Theranostic Systems

Schiff Base Aggregation-Induced Emission Luminogens for Sensing Applications: A Review

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