2020
DOI: 10.1161/circulationaha.120.047427
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An Ominous ECG Sign in Critical Care

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Cited by 13 publications
(14 citation statements)
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“…Several hypotheses have been contemplated, and some propose that SHS is an extreme manifestation of hyperadrenergic state that results in prolongation of repolarization. 5 This hypothesis is supported by the occurrence of SHS in Takotsubo cardiomyopathy and stellate ganglion block. 6,7 Scorpion venom consists of numerous toxins, of which α-toxin causes neuronal stimulation by inhibiting inactivation of the voltage-gated sodium channels.…”
Section: Discussionmentioning
confidence: 90%
“…Several hypotheses have been contemplated, and some propose that SHS is an extreme manifestation of hyperadrenergic state that results in prolongation of repolarization. 5 This hypothesis is supported by the occurrence of SHS in Takotsubo cardiomyopathy and stellate ganglion block. 6,7 Scorpion venom consists of numerous toxins, of which α-toxin causes neuronal stimulation by inhibiting inactivation of the voltage-gated sodium channels.…”
Section: Discussionmentioning
confidence: 90%
“…A recent case of Crinion et al showed the "spiked helmet" sign by a patient with septic shock, where however the upward shift preceding the QRS complex could have been given by a negative T wave, and not necessarily by an elevation of the isoelectric line. 6 Interobserver agreement should be investigated in future studies. The differential diagnoses for ST-elevations remain broad and should be scrutinized with attention.…”
Section: Discussionmentioning
confidence: 99%
“…1,3 The Spiked Helmet Sign (SHS) has been named for its resemblance to the Prussian military helmet, the Pickelhaube. 4 Though SHS mimics acute myocardial infarction, there is a characteristic upward shift in the baseline preceding the QRS because of delayed giant T-U waves. The ST-segment is in continuity with this shift completing the "helmet" of SHS, with QRS forming the spike on it.…”
Section: Commentarymentioning
confidence: 99%
“…First described in cases of acute abdominal or thoracic pathology, it has subsequently been reported in a variety of acute conditions like intracranial hemorrhage, sepsis, and metabolic derangements. 4 The mechanism is presumed to be a prolongation of repolarization similar to that seen in long QT syndrome secondary to catecholaminergic excess seen in these conditions. Recently, SHS has been described in association with Takotsubo cardiomyopathy also.…”
Section: Commentarymentioning
confidence: 99%