Abstract:Microsatellite instability (MSI) is one of the genetic abnormalities underlying endometrial carcinoma, especially endometrioid endometrial carcinoma (EEC). Microsatellite unstable endometrial carcinomas may be associated with multiple primary malignancies. We aimed to document the incidence and type of associated tumours in MSI/mismatch repair deficient (MMR-d) endometrial carcinomas at a single institution in South Africa. Methods: The study assessed EECs for the period 2009-2015 at a Johannesburg hospital an… Show more
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