An MAP Kinase Cascade Downstream of RGF/GLV Peptides and Their RGI Receptors Regulates Root Development

Abstract

Plant developmental processes require active cell-cell communication. Signaling peptides are now recognized as major players involved in many plant developmental and immunity programs. Currently, the cognate receptors for many signaling peptides have also been unraveled. Although we are starting to gain insights into some of the molecular components, the downstream pathway after ligand perception, however, is in most cases unknown (Oh et al., 2018).The family of Root Meristem Growth Factors (RGF)/GOLVEN (GLV), also known as CLE-Like, signaling peptides is composed of 11 members in Arabidopsis thaliana and has been mainly associated to root development (

A rulebook for peptide control of legume–microbe endosymbioses

“…Another family of root growth regulators are the RGF peptides, which are present in all root and rhizoid-forming bryophytes and plants but absent in green algae and the only sequenced lycophyte (Figure 3) [105,109]. This suggests an evolutionarily important role in a shift to a land-based habitat consistent with the roles of RGFs identified to date, including gravity sensing, lateral root initiation and emergence, interaction with plant pathogens, and a role in nodule formation [110][111][112]. Nodule and lateral root development are both regulated by similar developmental programs [113,114]; therefore, it is not surprising that peptide families such as CLE, CEP, or RGF, with important roles during root development, were co-opted to regulate the developmental programs associated with nodule formation [113,114].…”

Two phylogenetically unrelated peptide‐receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway inArabidopsis thaliana

“…This is likely due to the redundant activity of MPK3, as it is also phosphorylated upon treatment with GLV10p or TOLS2p (Fig. 5a) and known to act redundantly with MPK6 in diverse biological processes, including RGF1/GLV11 regulated RAM maintenance (Wang et al ., 2007; Cho et al ., 2008; Meng et al ., 2013; Lee et al ., 2019; Fernandez & Beeckman, 2020; Lu et al ., 2020; Shao et al ., 2020; Shen et al ., 2020).…”

Sulfated peptides and their receptors: Key regulators of plant development and stress adaptation

“…In the elongation zone, however, cells are able to elongate, but their division activities are lost ( Tsukagoshi et al., 2010 ). RGFs were also shown to regulate lateral root development in an MPK6-dependent manner ( Fernandez et al., 2013 , 2015 ; Fernandez and Beeckman, 2020 ). Auxin accumulates locally during lateral root initiation and development.…”