An m1A/m6A/m7G/m5C regulator-mediated methylation modification pattern and Landscape of immune microenvironment infiltration characterization in Lower-Grade Glioma cohorts from three continents based on machine learning
Abstract:Background: Although many studies have highlighted RNA modification processes such as N1-methyladenosine (m1A), N6-methyladenosine (m6A), N7-methylguanosine (m7G), and 5-methylcytosine methylation (m5C)’s role in the prognosis of patients suffering from different cancers, their prospective involvement in lower-grade gliomas (LGG) has not yet been outlined.
Methods: This work aims to assess the 64 genes related to m1A/m6A/m7G/m5C modification. Based on the expression of methylation-related regulators (MRRs), u… Show more
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