An isotope signature for diffuse idiopathic skeletal hyperostosis?

Abstract

Objectives Diffuse idiopathic skeletal hyperostosis (DISH) has recurrently been associated with a rich diet (high in protein and higher trophic level foods); however, very few studies have investigated this link using carbon and nitrogen (δ13C and δ15N) stable isotope analysis. This paper explores the relationship between DISH and diet in two Roman urban communities by analyzing individuals with and without DISH. Materials and methods δ13C and δ15N analysis carried out on collagen from 33 rib samples (No DISH: 27; early DISH: 4; DISH: 2) selected from individuals buried at the Romano‐British site of Baldock (UK), 41 rib samples (No DISH: 38; early DISH: 3) from individuals from the Catalan Roman site of Santa Caterina (Barcelona, Spain). Additionally, six faunal samples from Baldock and seven from Santa Caterina were analyzed. Results Standardized human isotope data from Santa Caterina show high δ15N probably associated to a diet combining terrestrial resources and freshwater fish. In contrast, isotope results from Baldock suggest a terrestrial‐based diet. Individuals with DISH do not show isotopic ratios indicative of rich diet and there is no correlation between stage of DISH development and δ13C and δ15N. Conclusion The results of this study suggest that individuals with DISH followed a similar or isotopically similar diet as those individuals without DISH in Baldock and in Santa Caterina and therefore, while DISH may have been influenced by individual's dietary habits, this is not reflected in their isotopic signature.

Prevalence of sacroiliac joint fusion in females and males depending on parity status

“…Furthermore, other types of pathologies that show ossification of ligaments and joints are also sexually dimorphic. Pathologies such as diffuse idiopathic skeletal hyperostosis (DISH) (Castells Navarro et al, 2022; Verlaan et al, 2007) and ankylosing spondylitis (AS) (Duyar, 2019) are more commonly found in males than females. Both DISH and AS include the ossification of spinal ligaments (Castells Navarro et al, 2022; Duyar, 2019), and AS specifically can impact the SI joints (Duyar, 2019; Šlaus et al, 2012).…”

“…Pathologies such as diffuse idiopathic skeletal hyperostosis (DISH) (Castells Navarro et al, 2022; Verlaan et al, 2007) and ankylosing spondylitis (AS) (Duyar, 2019) are more commonly found in males than females. Both DISH and AS include the ossification of spinal ligaments (Castells Navarro et al, 2022; Duyar, 2019), and AS specifically can impact the SI joints (Duyar, 2019; Šlaus et al, 2012). In other words, males are more prone to joint ossification than females are, and SI joint fusion may not be the exception to the rule.…”