An Isotope-Diagnostic Approach to Erdheim-Chester's Disease of the Heart

Abstract

Erdheim-Chester's disease is a form of histiocytic granulomatosis afflicting the skeletal system and various inner organs. Apart from incidental findings of involvement of various structures and tissues, a complete diagnostic workup to evaluate afflicted bodily parts is not known. The authors we present several specific isotope-diagnostic techniques of a case to support the identification of this rare multisystem infiltrative disease.

Radiopharmaceutical diagnosis of Erdheim–Chester's disease

“…We have delineated a case of xantho-granulomatous disease involving the ocular tissues with atypical myocardial involvement [3]. A novel therapeutic approach, involving non-steroidal anti-inflammatory drugs, and a full work-up using radioisotopes to aid the diagnosis have also been proposed [4]. This paper describes the advances in ECD in this respect, and proposes a specific diagnostic tool utilizing radiopharmaceuticals.…”