An iron fist in a velvet glove: The cooperation of a novel pyoverdine from Pseudomonas donghuensisP482 with 7‐hydroxytropolone is pivotal for its antibacterial activity
Sylwia Jafra,
Magdalena Jabłońska,
Tomasz Maciąg
et al.
Abstract:Pseudomonas donghuensis P482 exhibits broad antimicrobial activity against phytopathogens, including the soft rot bacteria of the Dickeya genus. Here, we report that under limited nutrient availability, the antibacterial activity of P. donghuensis P482 against Dickeya solani requires the reciprocal action of two iron scavengers: 7‐hydroxytropolone (7‐HT) and a newly characterized pyoverdine (PVDP482) and is quenched in the iron‐augmented environment. Further, we show that the biosynthesis of pyoverdine and 7‐H… Show more
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