An Invitro Study on Predicted Glycemic Index and Bioactive Component of Fortified - Bread Using Senna Auriculata

Gomathi, K.; F, Antony Xavier Bronson; J, Arun Kumar; Gayathri, S.; Emiyal, D

doi:10.26452/ijrps.v11i4.3140

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…The more the resistant starch in the variations, the lower is the EGI value of those variations of idli. The low GI, as well as high resistant starch, reduces the insulin resistance by lowering the blood glucose levels in diabetic patients as well improves the lipid metabolism and prevents cardiovascular diseases (Kannayiram et al, 2020). To summarize, the incorporation of 20 % raw O.basilicum seeds has resulted in a low glycaemic idli compared to all the other developed products.…”

Section: Estimation Of In Vitro Glycaemic Indexmentioning

confidence: 99%

A Comparative Study on the Carbohydrate proৎile and In-vitro Glycaemic Index of Processed Basil (Ocimum basilicum) Seeds Incorporated Idlis

R¹,

Nazni²

2020

ijrps

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The tiny black Ocimum basilicum seeds, also called as basil or sabja seeds aid to keep blood sugar levels under control by decelerating the carbohydrate conversion into glucose, a simple sugar. Raw and Steamed Ocimum basilicum seeds in the proportions of 5% (RV1, SV1), 10% (RV2, SV2), 15% (RV3, SV3) and 20% (RV4, SV4) of the black gram have been incorporated in the idli formulation. The results depicted that as the proportion of O.basilicum seeds increased the total carbohydrate and sugar values showed a decline, whereas the cellulose, hemicellulose and resistant starch values increased. At 120 minutes, the mean in vitro glycaemic index of the control idli was estimated to be 66.45 ± 0.03, while the mean estimated glycaemic index value of raw O.basilicum seed incorporated variations of idli namely RV1, RV2, RV3 and RV4 were 55.09 ± 0.02, 53.19 ± 0.02, 51.44 ± 0.01 and 48.09 ± 0.01 respectively. The mean estimated glycaemic index value of steamed O.basilicum seed incorporated variations of idli SV1 was found to be 62.72 ± 0.01, SV2 was 60.43 ± 0.01, SV3 was 58.16 ± 0.02, and SV4 was 56.63 ± 0.02 at 120 minutes. Hence it is opined that the 20% raw O.basilicum seed incorporated idli is very much low in estimated G.I values can be used in idli preparation as a means to offer a lower glycaemic index to the obese, diabetic and cardiac disorder populations.

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Section: Estimation Of In Vitro Glycaemic Indexmentioning

confidence: 99%

A Comparative Study on the Carbohydrate proৎile and In-vitro Glycaemic Index of Processed Basil (Ocimum basilicum) Seeds Incorporated Idlis

R¹,

Nazni²

2020

ijrps

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Glucose lowering effects by sago (Metroxylon sagu Rottb) resistant starches Type 2 and 4 in spontaneously type 2 diabetes, Goto kakizaki rat

Lokman

Bugam²,

Ibrahim³

et al. 2022

Preprint

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The beneficial effects of resistant starch (RS) consumption on health in terms of reducing postprandial hyperglycemia are evident. However, the potential of local Sarawak sago RS in regulating glucose has not been extensively studied. This study aims to identify glucose lowering effects of Sarawak sago RS namely, native unmodified (RS2) and chemically modified (RS4). An oral glucose tolerance test was performed before and after one-month treatment with sago RS2 and RS4 in spontaneously type 2 diabetes, goto kakizaki rat. The mechanisms involved were further explored by screening the in vitro inhibitory activities of α-Glucosidase and DPP-IV. Histopathology examination for pancreas, kidney and liver tissues was performed in response to sago RS treatment using hematoxylin and eosin (H&E) staining.The blood glucose area under the curve (AUC) in RS-treated groups was decreased and significant in RS2-treated group (p<0.05). Improved insulin AUC and higher glucagon like peptide (GLP-1) levels were observed in all RS-treated groups (p<0.05). Sago RS2 and RS4 might have potential roles in regulating glucose via α- Glucosidase and DPP-IV inhibitory activities by reducing glucose absorption in the intestine. For histopathology study, although insignificant, sago RS2 and RS4 attenuated lesion scores of pancreatic tissue whereas the liver and kidney tissues significantly showed lesser lesion scores as compared to the control diabetic group suggesting the potential of RS in reducing cell degeneration which indeed requires further validation.Findings of this study suggests the therapeutic potential of sago RS in the T2D management which may justify further investigation to be done.

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Postprandial glucose-lowering effects by sago (Metroxylon sagu Rottb.) resistant starch in spontaneously type 2 diabetes, Goto-Kakizaki rat

Lokman

Bugam²,

Ibrahim³

et al. 2023

Nutr Health

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Introduction: The beneficial effects of resistant starch (RS) consumption on health in terms of reducing postprandial hyperglycaemia are evident. However, the potential of local Sarawak sago RS in regulating glucose has not been extensively studied. Objectives: This study aims to identify glucose-lowering effects of Sarawak sago RS, namely native (RS2) and chemically modified (RS4). Methodology: An oral glucose tolerance test (OGTT) was performed before and after 1 month treatment with sago RS2 and RS4 in spontaneously type 2 diabetes (T2D), Goto-Kakizaki (GK) rat. The mechanisms involved were further explored by screening the in vitro inhibitory activities of α-glucosidase and dipeptidyl peptidase (DPP)-IV. Histopathology examination for pancreas, kidney and liver tissues was done in response to sago RS intake using haematoxylin and eosin (H&E) staining. Results and discussion: The incremental area under the curve (iAUC) for blood glucose in RS-treated groups was decreased and significant in RS2-treated group ( p < 0.05). Improved iAUC for insulin and higher glucagon-like peptide (GLP-1) levels were observed in all RS-treated groups ( p < 0.05). Both sago RS may have potential roles in regulating glucose via α- glucosidase and DPP-IV inhibitory activities by reducing intestinal glucose absorption. For histopathology, although insignificant, sago RS2 and RS4 attenuated lesion scores of pancreatic tissue whereas the liver and kidney tissues significantly showed lesser lesion scores compared to the control diabetic group suggesting the potential of RS in reducing cell degeneration. Conclusion: Findings of this study indicates that RS2 showed greater glucose-lowering effect when compared to RS4, thus the therapeutic potential in the T2D management should be further explored.

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An Invitro Study on Predicted Glycemic Index and Bioactive Component of Fortified - Bread Using Senna Auriculata

Cited by 3 publications

References 16 publications

A Comparative Study on the Carbohydrate proৎile and In-vitro Glycaemic Index of Processed Basil (Ocimum basilicum) Seeds Incorporated Idlis

A Comparative Study on the Carbohydrate proৎile and In-vitro Glycaemic Index of Processed Basil (Ocimum basilicum) Seeds Incorporated Idlis

Glucose lowering effects by sago (Metroxylon sagu Rottb) resistant starches Type 2 and 4 in spontaneously type 2 diabetes, Goto kakizaki rat

Postprandial glucose-lowering effects by sago (Metroxylon sagu Rottb.) resistant starch in spontaneously type 2 diabetes, Goto-Kakizaki rat

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