An investigation of the significance of Actinomycosis in tonsil disease

Lierop, A C van; Prescott, C.A.J.; Sinclair-Smith, C

doi:10.1016/j.ijporl.2007.08.021

Cited by 39 publications

(51 citation statements)

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“…However, there is no definite consensus on this issue. Although San et al (16) published in their article that Actinomyces was more common in men, in some other studies, it was reported that there was no difference in terms of gender (3,4,9). Erkiliç et al (14) found Actinomyces in 101 of the tonsillectomy materials of 1220 patients and found that there was a clear female predominance.…”

Section: Discussionmentioning

confidence: 98%

“…As a result, it is thought that Actinomyces settled in the tonsillar tissue can play a role in tonsillar hypertrophy. It is thought that the microorganisms settled in the tonsil produce some toxins, resulting in tonsil hypertrophy (3,10). On the other hand, Toh et al (15) found no significant relationship between the size of the tonsil and the presence of Actinomyces.…”

Section: Discussionmentioning

confidence: 99%

“…Human is the only natural reservoir (1). They mostly cause actinomycotic infections involving cervicofacial, abdominopelvic, and pulmonothoracic regions (2,3). Actinomyces israelii and Actinomyces naeslundii are the most prevalent species isolated in humans (4,5).…”

Section: Introductionmentioning

confidence: 99%

“…Although Actynomycetes are parts of the normal flora of tonsil tissue, primary tonsillitis can cause infection if the mucosal barrier is impaired and spread to the surrounding tissues with the proteolytic enzymes they produce (3,7).…”

Section: Introductionmentioning

confidence: 99%

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Relation of Actinomyces with Tonsillar Hypertrophy and Antibiotic Use

Kansu

2017

Turk Arch Otorhinolaryngol

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Objective: This study aimed to investigate the incidence of Actinomyces in tonsillar tissues of patients undergoing tonsillectomy and to determine the association among tonsillar volume, preoperative antibiotic use, and presence of Actinomyces in tonsil tissues. Methods:In this study, 142 patients who underwent tonsillectomy in last four years were included. Of the total patients, 97 (66.9%) were children and 47 (33.1%) were adults. The patients' age, sex, preoperative antibiotic use, tonsillar volume, and presence of actinomyces in tonsillar tissues were recorded.Results: Actinomyces was identified in tonsillar tissues of 16 (16.4%) pediatric and 21 (44.6%) adult patients. Of all pediatric patients positive for Actinomyces, 13 were males and three were females whereas of all adult patients positive for actinomyces, 14 were males and seven were females. Tonsillar tissue volumes in both pediatric and adult patients positive for Actinomyces were statistically higher than the Actinomyces negative ones. Antibiotic use was higher and the incidence of Actinomyces was lower in pediatric patients than in adult patients positive for Actinomyces. Conclusion:Our study results revealed that Actinomyces was prominent in adult patients with tonsillar hypertrophy. In addition, the frequent use of antibiotic decreased the incidence of Actinomyces in tonsillar tissues.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Relation of Actinomyces with Tonsillar Hypertrophy and Antibiotic Use

Kansu

2017

Turk Arch Otorhinolaryngol

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“…Bu lokalizasyonda infeksiyon, dil, larinks, hipofarinks, parotis, yumuşak damak, kafa derisi, paranazal sinüsler, tonsil ve temporal kemikte yerleşebilir. Tonsillektomi yapılan olgularda histopatolojik incelemeyle aktinomikoz tanısı alan hastaların oranı, çeşitli çalışmalarda %11 ile %97.7 arasında bildirilmiştir (6)(7)(8)(9)(10). Bu çalışmada 19 yıllık süre boyunca çe-şitli nedenlerle tonsillektomi yapılmış olgularda histopatolojik yöntemle saptanan aktinomikoz sıklığının araştırılması amaçlanmıştır.…”

Section: Introductionunclassified

Incidence of Actinomycosis in Tonsillectomized Patients: Histopathologic Data for 115 Cases and a Rare Localization of Actinomycosis in Tongue Base

Altuntaş¹,

Engin²,

Özer³

et al. 2010

Klimik Dergisi

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Cervicofacial Actinomycosis in Children

Şen¹,

Arısoy²,

Starke³

2021

Pediatric ENT Infections

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Actinomycosis is caused by Actinomyces spp., which are Gram-positive, non-acidfast, pleomorphic, non-spore-forming rods. They require anaerobic or microaerophilic environments for growth, and demonstrate branching, often appearing as beaded filaments [5,6]. Gram stain shows varying morphology from diphtheria bacillus-like appearance to a mycelial structure. The organisms are members of the Actinomycetales order, Actinomycetaceae family, Actinomyces genus [2]. Mycobacteria and Nocardia are also included in the Actinomycetales order, and histopathological and clinical differential diagnosis with the members of Actinomyces genus is sometimes difficult [1][2][3].Genus Actinomyces and the very closely related genus Nocardia were previously considered fungi [1,2]. The word Actinomyces means "ray-fungus," and the organisms resemble fungi because of their filamentous appearance. However, Actinomyces spp. are typical bacteria due to the structural features and antimicrobial drug susceptibility. They have much narrower filaments than the hyphae of the fungi. While the filaments of Actinomyces are easily fragmented, the tubular hyphae of the molds do not split and exhibit different branching patterns. Reproduction of Actinomyces is by binary fission, while fungi reproduce by spore and bud formation [2][3][4].Actinomyces spp. are natural members of the oropharyngeal, gastrointestinal, and genitourinary system microbiota [1,5,7]. Dental plaques, carious teeth, periodontal pockets, gingival crevices, tonsillar crypts, and saliva are colonized by Actinomyces species [8,9]. In a pediatric study performed on tonsillectomy tissue, Actinomyces colonization was detected at a rate of 12% [10].Twenty-six of the 49 known Actinomyces species have been implicated in human infections [7]. Actinomyces israelii is the most frequent cause of human disease, and Actinomyces gerencseriae, Actinomyces graevenitzii, Actinomyces meyeri, Actinomyces naeslundii, Actinomyces neuii, Actinomyces odontolyticus, Actinomyces radicidentis, Actinomyces radingae, Actinomyces turicensis, and Actinomyces viscosus were reported as the other leading Actinomyces species causing disease in humans [1,2,6,8]. Although A. israelii is the leading cause of actinomycosis, A. odontolyticus and A. naeslundii are the most common colonizing species in the oral cavity of children [11]. While Actinomyces bovis causes the disease known as "lumpy jaw" in cattle, it has been identified only in a single human case due to possible transmission via a lamb bite [12]. A study conducted in Germany found that A. israelii (42.0%) and A. gerencseriae (26.7%) were the most common species in 1997 culture-positive cases of human cervicofacial actinomycoses [13].Actinomyces spp. are co-pathogens, and require other bacteria to multiply, explaining why they are commonly found in tissues harboring other aerobic and/or anaerobic species. Thus, Actinomyces species are frequently isolated from clinical specimens together with other bacteria of the polymicrobial microbiota. They synergistically inh...

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An investigation of the significance of Actinomycosis in tonsil disease

Cited by 39 publications

References 6 publications

Relation of Actinomyces with Tonsillar Hypertrophy and Antibiotic Use

Relation of Actinomyces with Tonsillar Hypertrophy and Antibiotic Use

Incidence of Actinomycosis in Tonsillectomized Patients: Histopathologic Data for 115 Cases and a Rare Localization of Actinomycosis in Tongue Base

Cervicofacial Actinomycosis in Children

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