An investigation of the relationship between air emissions of volatile organic compounds and the incidence of cancer in Indiana counties

Boeglin, Michael L.; Wessels, Denise; Henshel, Diane S.

doi:10.1016/j.envres.2005.04.004

Cited by 166 publications

(81 citation statements)

References 27 publications

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“…8,9 Among the various indoor air pollutants, organic chemicals that easily volatize at room temperature called volatile organic compounds (VOCs), and semi-VOCs (SVOCs) often receive the most attention. Many VOCs are possible respiratory 10,11 and sensory irritants, 12,13 carcinogens, [14][15][16] developmental toxins, 10 neurotoxins, 17,18 hepatotoxins 19 and immunosuppressants 20 and may cause symptoms that manifest as sick building syndrome. 5,19 The broad range of adverse health effects reported are related to the amount of time spent inside buildings with poor air quality.…”

Section: Introductionmentioning

confidence: 99%

Airborne concentrations of volatile organic compounds in neonatal incubators

Prazad

Cortes²,

Puppala

et al. 2008

J Perinatol

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Objective: To identify and quantify airborne volatile organic compounds (VOCs) inside neonatal incubators during various modes of operation within the neonatal intensive care unit (NICU) environment.Study Design: Air samples were taken from 10 unoccupied incubators in four operational settings along with ambient air samples using air sampling canisters. The samples were analyzed following EPA TO-15 using a Tekmar AutoCan interfaced to Agilent 6890 Gas Chromatograph with a 5973 Mass Spectrometer calibrated for 60 EPA TO-15 method target compounds. Non-target compounds were tentatively identified using mass spectral interpretation and with a mass spectral library created by National Institute for Standards and Technology.Result: Two non-target compounds, 2-heptanone and n-butyl acetate, were found at elevated concentrations inside the incubators compared with ambient room air samples. Increase in temperature and addition of humidity produced further increased concentrations of these compounds. Their identities were verified by mass spectra and relative retention times using authentic standards. They were quantified using vinyl acetate and 2-hexanone as surrogate standards. Conclusion:The emission pattern of these two compounds and background measurements indicate that they originate inside the incubator. There is evidence that exposure to some VOCs may adversely impact the fetal and developing infants' health. Currently, as there is no definitive information available on the effects of acute or chronic lowlevel exposure to these compounds in neonates, future studies evaluating the health effects of neonatal exposure to these VOCs are needed.

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Section: Introductionmentioning

confidence: 99%

Airborne concentrations of volatile organic compounds in neonatal incubators

Prazad

Cortes²,

Puppala

et al. 2008

J Perinatol

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“…NMVOCs have an important influence on the formation of photochemical smog, secondary organic aerosols, and organic acids in the air, and they are severely harmful to human health (Boeglin et al, 2006). Therefore, research on the source and emission characteristics of NMVOCs has been an important issue in atmospheric chemistry studies, which not only provides scientific basis for the control of local photochemical smog pollution and for the prevention and control of acid rain, but also has a profound impact on systematic study on atmospheric chemical reactions, and on the assessment and forecast of the possible change of atmospheric environment on the global scale.…”

Section: Introductionmentioning

confidence: 99%

Spatial and temporal variation of historical anthropogenic NMVOCs emission inventories in China

2008

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Abstract. Multiyear emission inventories of anthropogenic, biomass open burning, and industrial and commercial consumption were primary emission sources. Besides, source contributions of NMVOCs emissions showed remarkable annual variation. However, emissions of these sources had been continuously increasing, which coincided well with China's economic growth. Spatial distribution of NMVOCs emissions illustrates that high emissions mainly concentrates in developed regions of northern, eastern and southern coastal areas, which produced more emissions than the relatively underdeveloped western and inland regions. Particularly, southeastern, northern, and central China covering 35.2% of China's territory, generated 59.4% of the total emissions, while the populous capital cities covering merely 4.5% of China's territory, accounted for 24.9% of the national emissions. Annual variation of regional emission intensity shows that emissions concentrating in urban areas tended to transfer to rural areas year by year. MoreCorrespondence to: S. D. Xie (sdxie@pku.edu.cn) over, eastern, southern, central, and northeastern China were typical areas of high emission intensity and had a tendency of expanding to the northwestern China, which revealed the transfer of emission-intensive plants to these areas, together with the increase of biomass open burning.

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“…VOCs are well known for their contribution toward global-scale environmental changes such as global warming, stratospheric ozone depletion, and photochemical ozone formation (Kavouras et al, 2013;Sahu, 2012;Evtyugina et al, 2009). It is also perceived that VOCs and their degradation products can be responsible for the high prevalence of various respiratory disorders and cancers (Sahu and Saxena, 2015;Yassaa et al, 2011;Wang and Zhao, 2008;Boeglin et al, 2006). Moreover, many members of VOCs can act as the source of odor nuisance on a regional scale (Lal et al, 2012;Sahu and Lal, 2006).…”

Section: Introductionmentioning

confidence: 99%

Quantitative Approaches for the Determination of Volatile Organic Compounds (VOC) and Its Performance Assessment in Terms of Solvent Types and the Related Matrix Effects

Ullah¹,

Kim²,

Szulejko³

et al. 2017

Asian J. Atmos. Environ

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For the quantitative analysis of volatile organic compounds (VOC), the use of a proper solvent is crucial to reduce the chance of biased results or effect of interference either in direct analysis by a gas chromatograph (GC) or with thermal desorption analysis due to matrix effects, e.g., the existence of a broad solvent peak tailing that overlaps early eluters. In this work, the relative performance of different solvents has been evaluated using standards containing 19 VOCs in three different solvents (methanol, pentane, and hexane). Comparison of the response factor of the detected VOCs confirms their means for methanol and hexane higher than that of pentane by 84% and 27%, respectively. In light of the solvent vapor pressure at the initial GC column temperature (35°C), the enhanced sensitivity in methanol suggests the potential role of solvent vapor expansion in the hot injector (split ON) which leads to solvent trapping on the column. In contrast, if the recurrent relationships between homologues were evaluated using an effective carbon number (ECN) additivity approach, the comparability assessed in terms of percent difference improved on the order of methanol (26.5%), hexane (6.73%), and pentane (5.24%). As such, the relative performance of GC can be affected considerably in the direct injection-based analysis of VOC due to the selection of solvent.

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An investigation of the relationship between air emissions of volatile organic compounds and the incidence of cancer in Indiana counties

Cited by 166 publications

References 27 publications

Airborne concentrations of volatile organic compounds in neonatal incubators

Airborne concentrations of volatile organic compounds in neonatal incubators

Spatial and temporal variation of historical anthropogenic NMVOCs emission inventories in China

Quantitative Approaches for the Determination of Volatile Organic Compounds (VOC) and Its Performance Assessment in Terms of Solvent Types and the Related Matrix Effects

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