An investigation of the effects of hydroxyapatite coatings on the fixation strength of cortical screws

Yıldırım, Ömer Selim; Aksakal, Bünyamin; Çelik, Haluk; Vangolu, Y.; Okur, Ali

doi:10.1016/j.medengphy.2004.10.006

Cited by 51 publications

(32 citation statements)

References 29 publications

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“…Several studies have proven HA to be an effective coating substance to increase bone-screw interfaces. 42,43 The size and shape of the deposited HA crystals in this study are similar to that in bone. Furthermore, nanoscale HA-coated implants may exceed micron-scale HA coatings in implant retention and histopathologic results.…”

supporting

confidence: 66%

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Johansson¹,

Jimbo²,

Kjellin³

et al. 2014

IJN

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Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bioinert and hydrophobic, and it does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano-modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n=24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n=24) were left uncoated (control). Half of the animals (n=12) were euthanized after 3 weeks of healing and the remaining (n=12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy, and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks ( P =0.05) and 12 weeks ( P =0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline hydroxyapatite coating to PEEK surfaces significantly increases its removal torque and biocompatibility.

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supporting

confidence: 66%

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Johansson¹,

Jimbo²,

Kjellin³

et al. 2014

IJN

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“…Figure 3 shows a schematic of the EPD set-up used, indicating also the steps followed to prepare the Au-patterned cathode (Wang & Hu 2003). Moreover, EPD has been used for the fabrication of uniform HA coatings on cortical screws for improved bone fixation and reduced risk of interfacial loosening (Yildirim et al 2005) and for achieving HA coatings with enhanced corrosion protection of metallic substrates in simulated body fluid (SBF) (Sridhar et al 2003;Wang et al 2005;Kwok et al 2009). In this regard, EPD enables us to replicate the contour of complex three-dimensional structures (topographies) if the scale of the features is large enough compared with the particles being deposited.…”

Section: Epd Of Hamentioning

confidence: 99%

Electrophoretic deposition of biomaterials

Boccaccını

Keim

et al. 2010

J. R. Soc. Interface.

613

412

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Electrophoretic deposition (EPD) is attracting increasing attention as an effective technique for the processing of biomaterials, specifically bioactive coatings and biomedical nanostructures. The well-known advantages of EPD for the production of a wide range of microstructures and nanostructures as well as unique and complex material combinations are being exploited, starting from well-dispersed suspensions of biomaterials in particulate form (microsized and nanoscale particles, nanotubes, nanoplatelets). EPD of biological entities such as enzymes, bacteria and cells is also being investigated. The review presents a comprehensive summary and discussion of relevant recent work on EPD describing the specific application of the technique in the processing of several biomaterials, focusing on (i) conventional bioactive (inorganic) coatings, e.g. hydroxyapatite or bioactive glass coatings on orthopaedic implants, and (ii) biomedical nanostructures, including biopolymer-ceramic nanocomposites, carbon nanotube coatings, tissue engineering scaffolds, deposition of proteins and other biological entities for sensors and advanced functional coatings. It is the intention to inform the reader on how EPD has become an important tool in advanced biomaterials processing, as a convenient alternative to conventional methods, and to present the potential of the technique to manipulate and control the deposition of a range of nanomaterials of interest in the biomedical and biotechnology fields.

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“…Their results suggest that coating with a biocompatible material enhances screw fixation, possibly by increasing the bone union ability as insertion/extraction torques are generated primarily by the shearing force and friction at the bone-screw interface. Other factors include the size of the screw and quality of bone in the interface (22). Yerby et al (21) studied the use of an injectable ceramic in the augmentation of a revision pedicle instrumentation.…”

Section: Discussionmentioning

confidence: 99%

“…The most important issue, however, is the coating method and its quality, as these factors have a crucial impact on implant fixation and bone ingrowth. In addition, coating screws with HA may be more economical and easier to apply compared with other coating methods, such as plasma spray coating (3,6,8,19) and electrophoretic deposition (22).…”

Section: Introductionmentioning

confidence: 99%

Biomechanical Comparisons of Pull Out Strengths After Pedicle Screw Augmentation with Hydroxyapatite, Calcium Phosphate, or Polymethylmethacrylate in the Cadaveric Spine

Rim

Park

et al. 2015

World Neurosurgery

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An investigation of the effects of hydroxyapatite coatings on the fixation strength of cortical screws

Cited by 51 publications

References 29 publications

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Electrophoretic deposition of biomaterials

Biomechanical Comparisons of Pull Out Strengths After Pedicle Screw Augmentation with Hydroxyapatite, Calcium Phosphate, or Polymethylmethacrylate in the Cadaveric Spine

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