An investigation of the association of benzodiazepines and other hypnotics with the incidence of falls in the elderly

Trewin, V. F.; Lawrence, C. J.; Veitch, G. B. A.

doi:10.1111/j.1365-2710.1992.tb01281.x

Cited by 31 publications

(17 citation statements)

References 13 publications

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“…This study examined the prevalence of prescription psychoactive drugs (sedatives/hypnotics, anxiolytics/tranquilizers, antidepressants, and prescription analgesics) and alcohol use and their association with selfreported falls. Consistent with the findings of other studies (Campbell et al, 1990;Campbell, 1991;Cwikel, 1992;Trewin et al, 1992), 26% of this sampie stated they had fallen at least once during the past year (range, 0-50). Analyses with logistic regression indicate that the risk for falls increases as one ages, has more illnesses, and takes psychoactive drugs.…”

Section: Discussionsupporting

confidence: 91%

“…The association of psychoactive medication use with falls among the noninstitutionalized elderly has been well documented (Campbell, 1991;Cwikel, 1992;Trewin et al, 1992;Ray et al, 1989Ray et al, , 1991. For a variety of reasons, older adults are particularly sensitive to the adverse side effects, such as diminished sensorium, dizziness, syncope, and orthostatic hypotension, produced by these substances.…”

Section: Introductionmentioning

confidence: 97%

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Psychoactive medication, alcohol use, and falls among older adults

et al. 1995

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The purposes of this study were to determine: (1) the prevalence of psychoactive medication and alcohol use and (2) the relationship among psychoactive medications, alcohol use, and falls in a sample of 1028 independently living women and men, aged 55 and older. Twenty-six percent of the sample reported falling, 28% were taking one or more psychoactive drugs, and 38% drank alcohol during the past year. Analyses with logistic regression indicate that predictors of falls were psychoactive drug use, age, and number of illnesses. Living alone, frequency of alcohol use, and gender were not significant predictors.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 97%

Psychoactive medication, alcohol use, and falls among older adults

et al. 1995

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“…The increased incidence of post-stroke fractures might be because stroke patients are particularly prone to accidental falls [6,7]. Stroke patients fall mainly towards their paretic side due to balance problems and detoriation in neuromuscular response, which leads to a reduced ability to protect themselves when they fall [23][24][25]. Another contributing risk factor may be the development of disuse osteoporosis on the paretic side [1][2][3]8,9,11,26,27].…”

Section: Discussionmentioning

confidence: 99%

Fractures after Stroke

Ramnemark

Nyberg

Borssén

et al. 1998

Osteoporosis International

273

213

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Fractures are a serious complication after stroke. Among patients with femoral neck fractures, a large subgroup have had a previous stroke. This study aimed to investigate the incidence of fractures after stroke. Included in the study were 1139 patients consecutively admitted for acute stroke. Fractures occurring from stroke onset until the end of the study or death were registered retrospectively. Hip fracture incidence was compared with corresponding rates from the general population. Patients were followed up for a total of 4132 patient-years (median 2.9 years). There were 154 fractures in 120 patients and median time between the onset of stroke and the first fracture was 24 months. Women had significantly more fractures than men (chi 2 = 15.6; p < 0.001). In patients with paresis most of the fractures affected the paretic side (chi 2 = 22.5; p < 0.001) and 84% of the fractures were caused by falls. Hip fracture was the most frequent fracture and the incidence was 2-4 times higher in stroke patients compared with the reference population. Fractures are thus a common complication after stroke. They are usually caused by falls and affect the paretic side. It is necessary to focus on the prevention of post-stroke fractures, including the prevention of both falls and osteoporosis.

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“…Concerned that this new cost‐sharing drug plan could have a negative impact on the use of effective and essential medications for older people, we investigated whether the consumption of nitrates, antihypertensive agents, and anticoagulants was affected by the introduction of this drug plan. As a comparison, we also studied changes in the consumption of benzodiazepines, medications that are not always considered essential and have been associated with falls in older people 7,8 . The population under study was residents of Quebec age 65 years and older and insured by the RAMQ for their medications for at least some time between 1992 and 1997.…”

mentioning

confidence: 99%

“…As a comparison, we also studied changes in the consumption of benzodiazepines, medications that are not always considered essential and have been associated with falls in older people. 7,8 The population under study was residents of Quebec age 65 years and older and insured by the RAMQ for their medications for at least some time between 1992 and 1997.…”

mentioning

confidence: 99%