An investigation of maternal anaemia among HIV infected pregnant women on antiretroviral treatment in Johannesburg, South Africa

Methazia, Jewelle; Ngamasana, Emery; Utembe, Wells; Ogunrombi, Modupe; Nyasulu, Peter

doi:10.11604/pamj.2020.37.93.22244

Cited by 5 publications

(8 citation statements)

References 33 publications

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“…Of the 14 included studies, three (SADHS 2016, SANHANES 2012, and NFCS 2005) [ 18 , 19 , 20 ] were national surveys conducted across South African geographic locations and provinces. Of the remaining studies, seven were regional surveys [ 29 , 30 , 31 , 32 , 33 , 34 , 35 ], and four were cohort studies [ 36 , 37 , 38 , 39 ]. More than 50% were conducted among rural populations [ 29 , 30 , 31 , 32 , 33 , 36 ], while five studies were from urban settings [ 34 , 35 , 37 , 38 , 39 ].…”

Section: Resultsmentioning

confidence: 99%

“…Of the remaining studies, seven were regional surveys [ 29 , 30 , 31 , 32 , 33 , 34 , 35 ], and four were cohort studies [ 36 , 37 , 38 , 39 ]. More than 50% were conducted among rural populations [ 29 , 30 , 31 , 32 , 33 , 36 ], while five studies were from urban settings [ 34 , 35 , 37 , 38 , 39 ].…”

Section: Resultsmentioning

confidence: 99%

“…Overall, ten studies reported prevalence of anaemia, ID, and IDA among WRA, while nine studies described prevalence in children under-5-years of age. Three studies measured prevalence of anaemia in pregnant women [ 18 , 35 , 39 ] and another three assessed anaemia in HIV-infected pregnant women [ 35 , 37 , 38 ]. Most of the studies were conducted among Black Africans [ 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 39 ].…”

Section: Resultsmentioning

confidence: 99%

“…Most of the studies were conducted among Black Africans [ 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 39 ]. Significant variability was observed between studies [ 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 ]. Methodologies were poorly reported in most studies, for example, consecutive sampling/convenience sampling was used in studies.…”

Section: Resultsmentioning

confidence: 99%

“…Anaemia prevalence in HIV-infected pregnant women was investigated in three studies, which were all conducted in urban locations [ 35 , 37 , 38 ]. A study conducted in Johannesburg estimated anaemia in HIV-infected pregnant women as 60.6% [ 37 ]; whereas Nandlal et al (2014) and Tunkyi et al (2016) reported a much higher prevalence of 64.2% [ 38 ] and 71.3% [ 35 ], respectively, in KZN province.…”

Section: Resultsmentioning

confidence: 99%

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Prevalence of Anaemia, Iron Deficiency, and Iron Deficiency Anaemia in Women of Reproductive Age and Children under 5 Years of Age in South Africa (1997–2021): A Systematic Review

Turawa

Awotiwon

Dhansay

et al. 2021

IJERPH

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Using a systematic review method, the prevalence of anaemia, iron deficiency (ID), and iron deficiency anaemia (IDA) in women of reproductive age (WRA) and children under 5 years of age was obtained to inform priorities in health planning and policy in South Africa. We searched electronic databases for articles published between 1997 and 2021. A total of 713 articles were identified, of which 14 articles comprising 9649 WRA and 4085 children were included. Since most of the included studies were of low quality, we did not pool data in a meta-analysis due to heterogeneity (I2 > 75%). In WRA, anaemia prevalence ranged from 22.0% to 44.0%; ID from 7.7% and 19.0%; and IDA from 10.5% to 9.7%. The prevalence of anaemia in pregnancy was 29.0% to 42.7%; and 60.6% to 71.3% in HIV-infected pregnant women. Three national surveys reported anaemia in children at 28.9%, 10.7%, and 61.3%, respectively. Overall, among the children under 5 years old, anaemia was more prevalent in 1-year-olds (52.0%) compared to the other age groups. Between 2005 and 2012, ID increased by 3.8% and IDA decreased by 83.2% in children. Anaemia in WRA and children under 5 years in South Africa was a moderate public health concern. Therefore, interventions addressing anaemia should be intensified, and policies on iron supplementation and food fortification need to be revised and aligned to the WHO multiple micronutrient supplementation recommendations.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Prevalence of Anaemia, Iron Deficiency, and Iron Deficiency Anaemia in Women of Reproductive Age and Children under 5 Years of Age in South Africa (1997–2021): A Systematic Review

Turawa

Awotiwon

Dhansay

et al. 2021

IJERPH

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Anemia and thrombocytopenia in HIV-positive pregnant women

Mozalyova

Самарина

Рассохин

2022

Journal of obstetrics and women's diseases

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BACKGROUND: During pregnancy and childbirth, anemia and thrombocytopenia are twice as common among HIV-positive women as in the general population. It has not been yet clear to what extent HIV affects the incidence of cytopenias, therefore, the correlation between the incidence and the HIV RNA level and CD4 count in HIV-positive pregnant women, as well as the role of antiretroviral therapy, requires further study. AIM: The aim of this study was to assess the effect of the HIV RNA level and CD4 count on the frequency of anemia and thrombocytopenia in HIV-positive pregnant women. MATERIALS AND METHODS: In this study, we analyzed social and demographic features, epidemiological personal history data, the frequency of pregnancy and delivery complications, and the timing of the initiation of antiretroviral therapy in 303 HIV-positive pregnant women, as well as the data of screening for HIV infection of their children. The study included 27 mother-child pairs with perinatal HIV transmission and 276 mother-child pairs without mother-to-child transmission of HIV. All pregnant women were divided into groups depending on the CD4 count and HIV RNA level. A comparative analysis of anemia and thrombocytopenia frequencies was carried out in the study groups. RESULTS: A direct correlation was revealed between the frequency of anemia and thrombocytopenia in HIV-positive pregnant women and markers of HIV infection: severe immunodeficiency (CD4 200 cells/l, p 0.01) and high HIV RNA levels (more than 100,000 copies / ml, p 0.01) in peripheral blood. CONCLUSIONS: We confirmed the high frequency of cytopenias in HIV-positive pregnant women, which exceeds the general population level. In addition, we demonstrated the effectiveness of prescribing antiretroviral therapy among women of reproductive age who planned to become pregnant or did not exclude the possibility of pregnancy (who did not use the effective methods of contraception), as a means of anemia and thrombocytopenia prevention during pregnancy.

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Faktor Risiko Dan Pencegahan Anemia Pada Wanita Usia Subur Di Berbagai Negara

Pamela,

Nurmala,

Ayu

2022

Ikesma

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Anemia adalah suatu permasalahan kesehatan masyarakat secara global. Wanita usia subur adalah salah satu yang terkena dampaknya. Diketahui sekitar 528 juta (29,4%) wanita di seluruh dunia yang melahirkan mengalami anemia. Tujuan dari review ini adalah untuk menetukan prevalensi anemia pada wanita usia subur di dunia, dan mengidentifikasi faktor risiko yang paling banyak terjadi pada anemia di kelompok ini serta pencegahan yang paling efektif. Jenis penelitian ini berupa narrative literature review dengan sumber jurnal sebanyak 40 artikel berasal dari PubMed, Google Scholar, Elsevier ,BMC dengan terbitan 2015-2020 yang dikumpulkan mulai januari-juni 2021 dan setelah melalui proses screening dan kesesuaian dengan kriteria inklusi penelitian maka diperoleh 10 rujukan yang digunakan dalam penelitian ini. Hasil penelitian menunjukan prevalensi anemia tertinggi adalah di negara berkembang dan tipe anemia yang paling sering terjadi pada kelompok wanita usia subur adalah anemia yang disebabkan oleh nutrisi dan anemia pada penyakit kronis. Peningkatan risiko pada anemia berhubungan dengan beberapa faktor antara lain dengan penggunaan sumber air sebagai air minum, kehamilan, infeksi malaria pada saat kehamilan, variabel dari jumlah anggota keluarga dalam rumah tangga, pendapatan rumah tangga dalam setiap bulan, riwayat infeksi parasit pada pencernaan, durasi menstruasi, dan indeks masa tubuh sesuai dengan usia. Risiko pada anemia defisiensi zat besi berhubungan signifikan (P= 0.05) dengan menikah pada usia muda (19 tahun) dan paritas yang lebih tinggi, riwayat keluarga yang memiliki anemia defisiensi zat besi dan frekuensi konsumsi daging yang tidak rutin. Semua faktor risiko yang teridentifikasi perlu dipertimbangkan dalam menentukan strategi pencegahan dan pengendalian anemia pada wanita usia subur. Kata Kunci: anemia, wanita usia subur, faktor risiko, pencegahan

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An investigation of maternal anaemia among HIV infected pregnant women on antiretroviral treatment in Johannesburg, South Africa

Cited by 5 publications

References 33 publications

Prevalence of Anaemia, Iron Deficiency, and Iron Deficiency Anaemia in Women of Reproductive Age and Children under 5 Years of Age in South Africa (1997–2021): A Systematic Review

Prevalence of Anaemia, Iron Deficiency, and Iron Deficiency Anaemia in Women of Reproductive Age and Children under 5 Years of Age in South Africa (1997–2021): A Systematic Review

Anemia and thrombocytopenia in HIV-positive pregnant women

Faktor Risiko Dan Pencegahan Anemia Pada Wanita Usia Subur Di Berbagai Negara

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