An Investigation of Finger and Manual Dexterity

Chan, Tam

doi:10.2466/pms.2000.90.2.537

Cited by 19 publications

(10 citation statements)

References 3 publications

(2 reference statements)

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“…Attention and processing speed were determined by the Test battery of Attentional Performance (TAP; Zimmermann & Fimm, 2004), the Paced Auditory Serial Addition Test (PASAT 3″; Gronwall & Sampson, 1974), and the Symbol Digit Modalities Test (SDMT; Smith, 1982) et al, 2000). Neurological assessments included the Expanded disability status scale (EDSS) (Kurtzke, 1983), the 9-Hole Peg Test (NHPT) (Backman et al, 1992;Chan, 2000), and the Timed-25 food walk (T25FW). We inverted cognitive test scores occasionally, so that higher values indicate always better performance.…”

Section: Neuropsychological and Neurological Examinationsmentioning

confidence: 99%

Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis

Silemek

Nolte

Pöttgen

et al. 2022

J of Neuroscience Research

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Multiple sclerosis (MS) is an inflammatory and demyelinating disease which leads to impairment in several functional systems including cognition. Alteration of brain networks is linked to disability and its progression. However, results are mostly cross‐sectional and yet contradictory as putative adaptive and maladaptive mechanisms were found. Here, we aimed to explore longitudinal reorganization of brain networks over 2‐years by combining diffusion tensor imaging (DTI), resting‐state functional MRI (fMRI), magnetoencephalography (MEG), and a comprehensive neuropsychological‐battery. In 37 relapsing‐remitting MS (RRMS) and 39 healthy‐controls, cognition remained stable over‐time. We reconstructed network models based on the three modalities and analyzed connectivity in relation to the hierarchical topology and functional subnetworks. Network models were compared across modalities and in their association with cognition using linear‐mixed‐effect‐regression models. Loss of hub connectivity and global reduction was observed on a structural level over‐years (p < .010), which was similar for functional MEG‐networks but not for fMRI‐networks. Structural hub connectivity increased in controls (p = .044), suggesting a physiological mechanism of healthy aging. Despite a general loss in structural connectivity in RRMS, hub connectivity was preserved (p = .002) over‐time in default‐mode‐network (DMN). MEG‐networks were similar to DTI and weakly correlated with fMRI in MS (p < .050). Lower structural (β between .23–.33) and both lower (β between .40–.59) and higher functional connectivity (β = −.54) in DMN was associated with poorer performance in attention and memory in RRMS (p < .001). MEG‐networks involved no association with cognition. Here, cognitive stability despite ongoing neurodegeneration might indicate a resilience mechanism of DMN hubs mimicking a physiological reorganization observed in healthy aging.

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Section: Neuropsychological and Neurological Examinationsmentioning

confidence: 99%

Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis

Silemek

Nolte

Pöttgen

et al. 2022

J of Neuroscience Research

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“…For descriptive purposes, we report SDMT values as SD from available norm data adjusted for sex, age and education (Köhler et al, 2017). 9-Hole Peg Test (NHPT) (Backman et al, 1992;Chan, 2000) and the Timed-25 food walk (T25FW) were used in the neurological assessment.…”

Section: Clinical Assessmentsmentioning

confidence: 99%

Delayed access to conscious processing in multiple sclerosis: Reduced cortical activation and impaired structural connectivity

Silemek

Ranjeva

Audoin

et al. 2021

Human Brain Mapping

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Although multiple sclerosis (MS) is frequently accompanied by visuo-cognitive impairment, especially functional brain mechanisms underlying this impairment are still not well understood. Consequently, we used a functional MRI (fMRI) backward masking task to study visual information processing stratifying unconscious and conscious in MS. Specifically, 30 persons with MS (pwMS) and 34 healthy controls (HC) were shown target stimuli followed by a mask presented 8-150 ms later and had to compare the target to a reference stimulus. Retinal integrity (via optical coherence tomography), optic tract integrity (visual evoked potential; VEP) and whole brain structural connectivity (probabilistic tractography) were assessed as complementary structural brain integrity markers. On a psychophysical level, pwMS reached conscious access later than HC (50 vs. 16 ms, p < .001). The delay increased with disease duration (p < .001, β = .37) and disability (p < .001, β = .24), but did not correlate with conscious information processing speed (Symbol digit modality test, β = .07, p = .817). No association was found for VEP and retinal integrity markers. Moreover, pwMS were characterized by decreased brain activation during unconscious processing compared with HC. No group differences were found during conscious processing. Finally, a complementary structural brain integrity analysis showed that a reduced fractional anisotropy in corpus callosum and an impaired connection between right insula and primary visual areas was related to delayed conscious access in pwMS. Our study revealed slowed conscious access to visual stimulus material in MS and a complex pattern of functional and structural alterations coupled to unconscious processing of/delayed conscious access to visual stimulus material in MS.

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“…It is an assessment involving insertion of a pin with a length of 25 mm, 3 mm in diameter within a predetermined length of time into a board on which 25 holes are arranged vertically. 25 The DASH is a 30-item patient-rated questionnaire of upper extremity disability and symptoms. Each question has five response choices, ranging from ''no difficulty or no symptom'' to ''unable to perform activity or very severe symptom.''…”

Section: Outcome Measuresmentioning

confidence: 99%

“…Activities include fine hand use, for example, ''performing the coordinated actions of handling objects, picking up, manipulating and releasing them using one's hand, fingers.'' 2 Dexterity in particular, which is defined as ''the skillful and controlled manipulation of a tool or an object by the fingers,'' 3,4 is considered essential for successfully performing tasks of daily living, work, school, play, and leisure. 5,6 As such, in a comprehensive assessment of upper extremity function, dexterity is an important component.…”

Section: Introductionmentioning

confidence: 99%

Validity and responsiveness of the Simple Test for Evaluating Hand Function

et al. 2017

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Introduction: Despite widespread use of the Simple Test for Evaluating Hand Function, we were unable to find studies to affirm the validity and responsiveness in patients with trauma and inflammatory diseases. The aim of this study was to demonstrate the criterion validity and responsiveness of the Simple Test for Evaluating Hand Function, a tool which is widely used in Japan. Methods: Thirty patients between the ages of 20 and 82 years with distal radius fracture (n ¼ 10), and cervical spondylosis myelopathy (n ¼ 20) were included in this study. Concurrent validity was tested by examining the correlation between Simple Test for Evaluating Hand Function, the Purdue Pegboard Test, and the Disabilities of the Arm, Shoulder and Hand questionnaire. In addition, standardized response means were calculated to compare the responsiveness of the Simple Test for Evaluating Hand Function with Purdue Pegboard Test and Disabilities of the Arm, Shoulder and Hand. Results: The correlation coefficient between Simple Test for Evaluating Hand Function and Purdue Pegboard Test was 0.70, and the correlation between Simple Test for Evaluating Hand Function and Disabilities of the Arm, Shoulder and Hand was À0.55 (p < 0.05). Standardized response mean shows that the Simple Test for Evaluating Hand Function (0.69) is more responsive than the Purdue Pegboard Test (0.53), and less responsive than Disabilities of the Arm, Shoulder and Hand (0.97). Conclusions: The Simple Test for Evaluating Hand Function demonstrates concurrent validity and responsiveness as a performance based assessment of dexterity in patients with distal radius fracture and cervical spondylosis. We conclude that the Simple Test for Evaluating Hand Function could be used as a measure of dexterity or clinical change after therapy intervention. The Purdue Pegboard Test may be used for patients with an occupation that requires integrated fine motor skills and bimanual activity, whereas the Simple Test for Evaluating Hand Function may be more suitable for patients who use a variety of unilateral grips such as pinch and span. The Simple Test for Evaluating Hand Function and Disabilities of the Arm, Shoulder and Hand can complement each other when measuring someone's activity and participation level.

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An Investigation of Finger and Manual Dexterity

Cited by 19 publications

References 3 publications

Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis

Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis

Delayed access to conscious processing in multiple sclerosis: Reduced cortical activation and impaired structural connectivity

Validity and responsiveness of the Simple Test for Evaluating Hand Function

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