An Investigation Into the Effects of Long‐Term 50‐Hz Power‐Frequency Electromagnetic Field Exposure on Hematogram, Blood Chemistry, Fibrosis, and Oxidant Stress Status in the Liver and the Kidney From Sprague–Dawley Rats

Abstract

Power‐frequency electromagnetic fields (PF‐EMFs) at 50 Hz are potential health risk factors. This study aimed to explore the effects of long‐term exposure to 50‐Hz PF‐EMFs on general physiological conditions in Sprague–Dawley (SD) rats. During a 24‐week exposure period, the body mass and water and food intake of the animals were recorded regularly. The hematologic parameters were detected every 12 weeks, and blood chemistry analyses were performed every 4 weeks. After sacrifice, morphology was identified by hematoxylin–eosin, Masson, and immunohistochemical staining. Fibrosis‐related gene expression and oxidative stress status were also detected. Compared with the control group, exposure to 30, 100, or 500 μT PF‐EMF did not exert any effect on body mass, food intake, or water intake. Similarly, no significant differences were found in hematologic parameters or blood chemistry analyses among these groups. Furthermore, morphological assays showed that exposure to PF‐EMFs had no influence on the structure of the liver or kidney. Finally, fibrosis‐related gene expression and oxidative stress status were unaltered by PF‐EMF exposure. The present study indicates that 24 weeks of exposure to PF‐EMFs at intensities of 30, 100, or 500 μT might not affect hemograms, blood chemistry, fibrosis, or oxidative stress in the liver or kidney in SD rats. © 2020 Bioelectromagnetics Society

Biological Effects of Magnetic Storms and ELF Magnetic Fields

“…The effects of background EMFs largely depend on the animal species (Figure 5, Table 2). ELF-MFs with characteristics close to the background EMF of cities f( 50)b(30-500)B(0.001)t(24 weeks), in the case of rats, even with long-term exposure did not affect body weight, water consumption, leukocyte blood count, expression of aminotransferases, Ca 2+ concentrations and Mg 2+ in the blood, or functions and structure of the kidneys and liver [222]. Birds, large ungulates, and humans are more sensitive to EMFs (see below).…”

“…Laboratory studies rarely exceed the time threshold of 1-2 days of exposure (~10 5 s, Figure 6). Studies of several weeks or months are very rare [222]. This limits studies to the frequency range (10 −4 -10 −3 Hz) characteristic of magnetic storms.…”

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