2020
DOI: 10.1101/2020.08.25.264457
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An investigation into the critical role of fibre orientation in the ultimate tensile strength and stiffness of human carotid plaque caps

Abstract: The development and subsequent rupture of atherosclerotic plaques in human carotid arteries is a major cause of ischemic stroke. Mechanical characterization of atherosclerotic plaques can aid our understanding of this rupture risk. Despite this however, experimental studies on human atherosclerotic carotid plaques, and fibrous plaque caps in particular, are very limited. This study aims to provide further insights into atherosclerotic plaque rupture by mechanically testing human fibrous plaque caps, the regio… Show more

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