An Introduction to Bio‐nanohybrid Materials

Ruiz‐Hitzky, Eduardo; Darder, Margarita; Aranda, Pîlar

doi:10.1002/9783527621446.ch1

Cited by 30 publications

(34 citation statements)

References 214 publications

(227 reference statements)

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“…Researchers from the Toyota company demonstrated by using natural clay montmorillonite in the early 1990s that it reinforced notably, improved dimensional stability, water and gas barrier properties of naylon-6 at amount of few percentages when was properly exfoliated into individual nanoparticles [6][7][8]. The same effects occur, as shown by many examples in reviews [1,2], for composites made of biopolymers. According to the classification suggested in [2], composites consisting of a constituent of biological origin and inorganic nanoparticles were classed as bionanocomposites, of synthetic polymers and nanoparticles, as nanocomposites, while biocomposites and composites, respectively, include filler of which dimension stands out above the nanosized particles.…”

Section: Introductionmentioning

confidence: 52%

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Chitosan bionanocomposites prepared in the self-organized regime

Postnova

Sarin

Силантьев

et al. 2015

Pure and Applied Chemistry

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Bionanocomposites in the self-organized regime are prepared when chitosan is gradually charged in the course of progressive change of pH by hydrolyzing D-glucono-δ-lactone in solutions of nanoparticles bearing negative charges on their surface. This novel approach is applicable to the formation of monolithic hydrogels and films. Here bionanocomposites of chitosan with clay nanoparticles of saponite and sepiolite having various geometry and with oxidized multiwall carbon nanotubes are considered. Structural organization of hydrogels and films is studied by scanning and transmission electron microscopy as well as small angle X-ray scattering. Jellification is caused by generation of three-dimensional network from fibrils, whereas films have pronounced stratified layer (nacre-like) structure from stacked nanoparticles and aligned chitosan macromolecules. Special attention is paid to mechanical properties of films that are improved drastically with introducing nanoparticles.

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Section: Introductionmentioning

confidence: 52%

“…Bionanocomposites are novel class of nanomaterials that consist of a constituent of biological origin and inorganic nanoparticles with at least one of dimensions in the range of 1-100 nm [1][2][3]. Nowadays they receive more and more attention because of an opportunity to be an alternative to the synthetic polymers.…”

Section: Introductionmentioning

confidence: 99%

Chitosan bionanocomposites prepared in the self-organized regime

Postnova

Sarin

Силантьев

et al. 2015

Pure and Applied Chemistry

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“…These minerals have been implicated in the prebiotic synthesis of biomolecules at the origin of life8. Because of their functional properties, bionanohybrid and bionanocomposite materials resulting from the combination of biopolymers with nanoparticulate solids such as clay minerals9101112 represent alluring prospects for biomedical applications13141516, such as biosensors, scaffolds for tissue engineering, effective drug-delivery nanovehicles, vaccination, and wound dressings171819202122232425262728.…”

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confidence: 99%

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

Castro-Smirnov

Piétrement

Aranda

et al. 2016

Sci Rep

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Nanofibers of sepiolite, a natural silicate belonging to the clay minerals family, might constitute a potential promising nanocarrier for the non-viral transfer of bio-molecules. We show here that sepiolite nanofibers efficiently bind different types of DNA molecules through electrostatic interactions, hydrogen bonding, cation bridges, and van der Waals forces. Moreover, Fourier-transform infrared spectroscopy identified the external silanol groups as the main sites of interaction with the DNA. Furthermore, as a proof of concept, we show that sepiolite is able to stably transfer plasmid DNA into mammalian cells and that the efficiency can be optimized. Indeed, sonication of sepiolite 100-fold stimulated DNA transfection efficiency. These results open the way to the use of sepiolite-based biohybrids as a novel class of nanoplatform for gene transfer with potential clinical applications.

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“…The main objective of this chapter focuses on clay-chitosan interactions but it is worthy to note a short reference to chitosan bio-nanocomposites based on other solids mainly present as nanoparticles (NPs) [2,4,120]. In this way, chitosan has been also employed to develop bio-nanocomposites based on nanoparticulate inorganic solids alone (Table 14.1) or in combination with clays in ternary systems.…”

Section: Functional Bio-nanocomposites Based On Chitosanmentioning

confidence: 99%

Chitosan-Clay Bio-Nanocomposites

Darder

Ruiz‐Hitzky

2012

Environmental Silicate Nano-Biocomposites

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The present review chapter includes an overview on the current state-of-art of chitosan-clay based bio-nanocomposites. In the same way than conventional nanocomposites, these biohybrid materials also exhibit both structural and functional properties together with biocompatibility and biodegradability, which can be of great interest for different applications. Four main areas of interest have been identified showing examples of applications as green nanocomposites, bio-nanocomposites addressed to biomedical purposes (tissue engineering and drug delivery), environmental remediation and electroanalytical devices. Finally, examples of bio-nanocomposites based on chitosan assembled to other inorganic solids have been introduced to show the versatility of this biopolymer for development of diverse type of advanced functional materials.

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An Introduction to Bio‐nanohybrid Materials

Cited by 30 publications

References 214 publications

Chitosan bionanocomposites prepared in the self-organized regime

Chitosan bionanocomposites prepared in the self-organized regime

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

Chitosan-Clay Bio-Nanocomposites

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