An intervention to increase hepatitis C virus diagnosis and treatment uptake among people in custody in Iran

Hariri, Sanam; Alavi, Maryam; Roshandel, Gholamreza; Mohammadi, Zahra; Fazel, Abdolreza; Amiriani, Taghi; Bazazan, Abolfazl; Motamed-Gorji, Nazgol; Sohrabpour, Amirali; Merat, Shahin; Malekzadeh, Reza

doi:10.1016/j.drugpo.2021.103269

Cited by 2 publications

(2 citation statements)

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“…9 Hepatitis B and C prevalence among people in custody Additionally, investigations in other regions, such as Gorgan and Karaj, revealed HCV antibody and RNA prevalence rates ranging from 6.7% to 5.2% and 4.6% to 3.4%, respectively. 10,11 A nationwide study covering 55 prisons in Iran found the prevalence of hepatitis B and C among people in custody with IV drug use to be 40.52% and 2.56%, respectively 12 A meta-analysis published in 2016 estimated the prevalence of HBV infection in the general Iranian population to be 2.2%. 13 Considering the distinct characteristics and epidemiological variations between hepatitis B and C, it becomes imperative to prioritize the prevention and management of hepatitis C in Iran, particularly due to the absence of a vaccine.…”

Section: Introductionmentioning

confidence: 99%

“… 9 Additionally, investigations in other regions, such as Gorgan and Karaj, revealed HCV antibody and RNA prevalence rates ranging from 6.7% to 5.2% and 4.6% to 3.4%, respectively. 10 , 11 A nationwide study covering 55 prisons in Iran found the prevalence of hepatitis B and C among people in custody with IV drug use to be 40.52% and 2.56%, respectively 12 A meta-analysis published in 2016 estimated the prevalence of HBV infection in the general Iranian population to be 2.2%. 13 …”

Section: Introductionmentioning

confidence: 99%

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Seroepidemiological Investigation of Hepatitis B and C Prevalence and Associated Factors Among People in Custody at Zahedan Central Prison

Metanat,

Almasi,

Sepehri Rad

et al. 2024

Arch Iran Med

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<strong data-sider-select-id="c7b9fc04-dfc5-47a4-9274-a7bdb03912d2">Background: On a global scale, approximately 350 million are affected by hepatitis B, and 71 million by hepatitis C. People in custody face elevated risks for these infections. The prevalence and risk factors in Iranian prisons are insufficiently documented. The principal objective of this study was to ascertain the prevalence of hepatitis B and C, coupled with the identification of pertinent influencing factors, within the confines of Zahedan central prison, situated in the southeastern region of Iran. <strong data-sider-select-id="ca1666cf-17d2-491a-b1f8-744c6f53fa8d">Methods: In 2019, we conducted an analytical cross-sectional study involving 407 people in custody, using stratified random sampling. To definitively diagnose hepatitis C virus (HCV) infection (P<0.05), a checklist developed by the researchers, along with enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) techniques, were employed. <strong data-sider-select-id="989ae849-ed0d-4766-beea-3cfb6f54d194">Results: This study comprised 406 participants (96.3% male) with a median age of 32 years (27-38). Approximately 62% were married, and a substantial proportion of the participants had low education levels (47%), unemployment (64%), and belonged to the Baloch ethnicity (64%). The overall prevalence of hepatitis C and B infections was 2.7% and 10.6%, respectively. Tattooing (adjusted odds ratio [AOR]: 2.07, 95% CI: 1.9-4.5) and marriage (AOR: 1.78, 95% CI: 1.05-3.04) were identified as risk factors for hepatitis B. Moreover, hepatitis C showed a statistically significant association with a family history of hepatitis B and C (AOR: 3.31, 95% CI: 3.93-24.64) and intravenous (IV) drug use (AOR: 7.01, 95% CI: 1.52-32.78) according to the multivariable logistic regression analysis. <strong data-sider-select-id="c19f6e91-24c2-481f-845e-0fc4baec1825">Conclusion: The prevalence of hepatitis B and C was higher among people in custody in Zahedan central prison. Consequently, targeted interventions are vital to address and reduce viral hepatitis burden in custodial settings.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Seroepidemiological Investigation of Hepatitis B and C Prevalence and Associated Factors Among People in Custody at Zahedan Central Prison

Metanat,

Almasi,

Sepehri Rad

et al. 2024

Arch Iran Med

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Towards hepatitis C virus elimination in Iran: A blueprint for comprehensive strategies

Mousavi,

Alavi,

Delavari

et al. 2024

Journal of Viral Hepatitis

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The hepatitis C virus (HCV) continues to pose a significant public health challenge in Iran, mirroring a worldwide concern. This situation calls for a cohesive strategy that aligns with the World Health Organization's (WHO) goals for HCV elimination by 2030. Central to this strategy is targeting high‐risk groups, notably people who inject drugs and prisoners, with prevention, screening and treatment. The deployment of point‐of‐care testing and treatments in prisons and harm reduction facilities is vital. The adoption of cost‐effective generic direct‐acting antivirals represents a major step forward. Furthermore, innovative educational initiatives for healthcare providers and awareness campaigns for the public are critical. Additionally, tackling stigma, ensuring treatment affordability and upholding strict surveillance and data management, coupled with ongoing policy reviews, are vital components. This comprehensive and integrated approach is designed to drive Iran towards eliminating HCV and can serve as a blueprint for other countries with similar challenges.

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An intervention to increase hepatitis C virus diagnosis and treatment uptake among people in custody in Iran

Cited by 2 publications

References 51 publications

Seroepidemiological Investigation of Hepatitis B and C Prevalence and Associated Factors Among People in Custody at Zahedan Central Prison

Seroepidemiological Investigation of Hepatitis B and C Prevalence and Associated Factors Among People in Custody at Zahedan Central Prison

Towards hepatitis C virus elimination in Iran: A blueprint for comprehensive strategies

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