Data from reporting systems around the world document that non-infectious hazards are the leading cause of serious morbidity or mortality resulting from blood transfusion. Among these non-infectious hazards, mis-transfusion represents the most frequently observed serious hazard and occurs at an estimated rate of 1 in 14,000 transfusions. Mistransfusion events result from "lapse errors" (slip ups) rather than cognitive mistakes.
Case Summary-Ms JohnstonOn a Thursday evening, you are paged to consult on the management of a patient (Mary Johnston) who has received incompatible blood. The patient is a 48-year-old woman who underwent surgery that morning for removal of a 2 cm, right para-renal mass. The surgery was uncomplicated and a frozen-section pathology specimen was read as a benign adenoma. She received 2.8 L of crystalloid solution during surgery. Post-operatively, her hematocrit was found to be 24% and she was given one unit of group A packed RBCs over 2 hours. Towards the end of the transfusion, she developed a shaking chill and her temperature rose from 99°F to 101°F. Her urine was red as a result of the renal surgery. A blood culture and complete blood count (CBC) were sent and the CBC specimen was reported as hemolyzed with a Hct = 24%. A transfusion reaction evaluation was sent to the blood bank accompanied by the empty blood bag and a freshly drawn post-transfusion specimen. The blood bank called back to report that a "wrong blood transfusion" had likely occurred. The name and medical record number attached to the empty blood bag tag (Mary Johnson, MRN 2395783) did not match that on the post-transfusion specimen (Mary Johnston, MRN 2395837). There was no pre-op sample on file for