“…In recent years, ANN, GAN, and other DL technologies have advanced swiftly and occasionally outpaced conventional ML. The use of DL in NM, referring to the physics part, includes disease diagnosis using PET [19], SPECT [20,21], imaging physics using PET [22], SPECT [23], image reconstruction using PET [24], SPECT [25], image denoising using PET [26,27], SPECT [28], image segmentation using PET [29], SPECT [30], and image classification using PET [31], SPECT [32]. Similar ideas are presented in [2,[33][34][35], where examples of specific ML capabilities include automated image segmentation, pre-analysis, and quantitation, radiomic feature extraction from image data, image reconstruction, case triage and reporting prioritization, research and data mining, and natural language processing.…”