The implementation of potentiostats as portable and communicated devices has reached significant progress to benefit research, industry, and education. The Internet of Things (IoT) is a good opportunity to interconnect devices such as the potentiostats together with electronics, communication technologies, and chemistry into a single system. This work proposes a network for potentiostats using machine-tomachine (M2M) protocols, modifying its functioning mechanism in the broker to check the payload of the message that passes through it and synchronize the sensors depending on its content. Although one sensor can be synchronized directly to another, the broker decides which sensor to pair. This modification was made in the M2M protocol algorithm, both in the Broker and in the Client (sensor). In addition to this, the network uses an interconnection architecture of IoT smart networks of proximity with centralized management. The results of the tests carried out showed that the use of a modified M2M such as the one proposed in the architecture allows synchronization and comparison of the measurements of several sensors in real-time.