An Integrated Simulation Approach and Experimental Research on Microwave Induced Thermo-Acoustic Tomography System

Song, Jian; Zhao, Zhiqin; Wang, Jin Guo; Zhu, Xiao; Wu, Jingwen; Nie, Zai Ping; Liu, Qing

doi:10.2528/pier13041704

Cited by 21 publications

(6 citation statements)

References 27 publications

(38 reference statements)

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“…Combining the measured results with the reported data of tissue properties with CNTs, a numerical breast model is established. An integrated simulation approach [18] including microwave field and acoustic field is performed to verify the imaging contrast enhancement. To better evaluate the performance of CNTs, tissue mimicking materials with different concentrations of CNTs are made and tested in a MITAT experimental system, corresponding with the simulation results to evaluate the imaging contrast enhancement caused by CNTs.…”

Section: Evaluation Of Contrast Enhancement By Carbonmentioning

confidence: 99%

Evaluation of Contrast Enhancement by Carbon Nanotubes for Microwave-Induced Thermoacoustic Tomography

Song

Zhao

Wang

et al. 2015

IEEE Trans. Biomed. Eng.

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Microwave-induced thermoacoustic tomography (MITAT) is a hybrid method which constructs images with ultrasound spatial resolution while exploiting dielectric contrast at microwave frequency. It has great potential in biomedical imaging especially in early breast cancer detection. The detection of early stage breast tumor in MITAT is challenged by the moderate endogenous dielectric contrast between malignant and healthy glandular tissues. In order to overcome this limitation, the performance of using carbon nanotubes (CNTs) as an imaging contrast enhancement agent is evaluated. First, the influences in dielectric and acoustic properties caused by CNTs are measured. Second, based on the measurements and the published data, numerical breast phantom is created and then used to explore the contrast enhancing effect of CNTs for MITAT, by an integrated simulation approach in both electromagnetic and acoustic field. With an experimental MITAT system, the thermoacoustic responses of tissue mimicking materials with different CNTs concentrations are also quantitatively investigated. Finally, the effectiveness of the contrast agent is also validated experimentally by using a MITAT system. The results show that the using of the dielectric contrast agent can effectively enhance the contrast of the MITAT image.

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Section: Evaluation Of Contrast Enhancement By Carbonmentioning

confidence: 99%

Evaluation of Contrast Enhancement by Carbon Nanotubes for Microwave-Induced Thermoacoustic Tomography

Song

Zhao

Wang

et al. 2015

IEEE Trans. Biomed. Eng.

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“…Fig. 4(b) shows a sketch map of the MITAT system which has been illustrated in [20,21]. The pulse width of the microwave generator is adjustable.…”

Section: Methodsmentioning

confidence: 99%

Analysis of Short Pulse Impacting on Microwave Induced Thermo-Acoustic Tomography

Liu¹,

Zhao²,

Zhu³

et al. 2016

PIER C

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Abstract-Microwave induced thermo-acoustic tomography (MITAT) is a developing technique for biomedical applications, especially for early breast cancer detection. In this paper, impacts of short microwave pulse on thermo-acoustic (TA) signals are analyzed and verified through some experimental comparisons. In these experiments, short microwave pulses with widths of 10 ns and 500 ns are employed as radiation resources. TA signals generated from a cubic sample are analyzed in both time-and frequency-domain. A trapezoid sample is also performed for experimental comparing. Different from previous literature, the effects of rising edge of radiation microwave pulse have been intensively studied. Experimental results demonstrate that shorter rising edge duration conducts broader bandwidth of TA signal, which give rise to better spatial resolution for tomography imaging.

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“…So, the microwave absorption distribution is mainly determined by the conductivity distribution. By using the integrated simulation approach, 31 the induced ultrasonic signals are generated and received by the surrounded transducer array. The transducer array has a total of 200 elements.…”

Section: D a Tumor Target Embedded In The Anatomically Realistic Nmentioning

confidence: 99%

Reducing the effects of acoustic heterogeneity with an iterative reconstruction method from experimental data in microwave induced thermoacoustic tomography

et al. 2015

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The distortions caused by the acoustic heterogeneity can be efficiently corrected by utilizing the velocity distribution estimated by the iterative reconstruction method. The advantage of the iterative reconstruction method over the existing correction methods is that it is successful in improving the quality of the image of microwave absorption distribution without increasing the system complexity.

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An Integrated Simulation Approach and Experimental Research on Microwave Induced Thermo-Acoustic Tomography System

Cited by 21 publications

References 27 publications

Evaluation of Contrast Enhancement by Carbon Nanotubes for Microwave-Induced Thermoacoustic Tomography

Evaluation of Contrast Enhancement by Carbon Nanotubes for Microwave-Induced Thermoacoustic Tomography

Analysis of Short Pulse Impacting on Microwave Induced Thermo-Acoustic Tomography

Reducing the effects of acoustic heterogeneity with an iterative reconstruction method from experimental data in microwave induced thermoacoustic tomography

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