An integrated proteomics and metabolomics approach to assess graft quality and predict early allograft dysfunction after liver transplantation: a retrospective cohort study
Yimou Lin,
Haitao Huang,
Jiaying Cao
et al.
Abstract:Background:
Early allograft dysfunction (EAD) is a common complication after liver transplantation (LT) and is associated with poor prognosis. Graft itself plays a major role in the development of EAD. We aimed to reveal the EAD-specific molecular profiles to assess graft quality and establish EAD predictive models.
Methods:
A total of 223 patients who underwent LT were enrolled and divided into training (n=73) and validation (n=150) sets. In the traini… Show more
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