An integrated One Health framework for holistic evaluation of risks from antifungal agents in a large-scale multi-city study using post-acquisition mass spectral data mining and wastewater-based epidemiology pipelines
Abstract:A new analytical framework for retrospective mass spectral data mining for antifungal (AFs) agents was developed as part of One Health framework for holistic evaluation of risks from AFs. Post-acquisition data mining of mass spectral repository obtained with a maXis HD QToF mass spectrometer, retrospective quantification and confirmation using bbCID method was undertaken. A large scale, multi-city spatiotemporal profiling programme of antifungal agents was undertaken in the Avon River catchment, South-West Eng… Show more
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