2020
DOI: 10.1039/d0an00251h
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An integrated microfluidic platform for selective and real-time detection of thrombin biomarkers using a graphene FET

Abstract: Continuous and real-time detection of protein biomarker using a microfluidic graphene-based transistor functionalized with thrombin-binding aptamers.

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Cited by 57 publications
(44 citation statements)
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“…Although Ag/AgCl demonstrates the best performance in terms of the operating voltage, gate leakage and gate hysteresis, in-plane gold electrode was used throughout the experiments as it gives the highest uniformity of the charge neutrality point among the devices on a single chip. Moreover, the in-plane configuration of the gold electrode which can be fabricated at the same lithography step as the source and drain electrodes enhances the compactness of the setup and allows the potential integration with the microfluidic platform [ 8 ].…”
Section: Resultsmentioning
confidence: 99%
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“…Although Ag/AgCl demonstrates the best performance in terms of the operating voltage, gate leakage and gate hysteresis, in-plane gold electrode was used throughout the experiments as it gives the highest uniformity of the charge neutrality point among the devices on a single chip. Moreover, the in-plane configuration of the gold electrode which can be fabricated at the same lithography step as the source and drain electrodes enhances the compactness of the setup and allows the potential integration with the microfluidic platform [ 8 ].…”
Section: Resultsmentioning
confidence: 99%
“…The Raman spectra for the PTDA-modified graphene were taken at 3 different spots on the surface. Figure 5 B shows the Raman spectra of the blank and the PTDA-functionalized graphene where the G-band split at around 1628 cm −1 indicates the anchoring of the PTDAs by π-π stacking interaction between the pyrene ring of the PTDA and the basal plane of graphene [ 8 ].…”
Section: Resultsmentioning
confidence: 99%
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