An Integrated Health Risk Assessment Approach to the Study of Mining Sites Contaminated with Arsenic and Lead

Jasso-Pineda, Yolanda; Espinosa-Reyes, Guillermo; González-Mille, Donaji J.; Razo-Soto, Israel; Carrizales, Leticia; Torres-Dosal, Arturo; Mejía-Saavedra, Jesús; Monroy, Marcos; Martínez, Fernando D.

doi:10.1897/ieam_2006-018

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“…2b). Bajpayee et al (2002) reported a reference value of 4 for OTM in adults, similar to the OTM of 3.2 and 3.9 observed by Yáñez et al (2003) and Jasso-Pineda et al (2007), respectively, in children residing in Matehuala (control group).…”

Section: Resultssupporting

confidence: 70%

“…In the same control group from Matehuala, the average TL was 41.7, while the children and adults from the mine zone of La Aurora showed 40.9 and 41.8 µm, respectively. In the exposed group of Villa de la Paz, studied by Yáñez et al (2003) and Jasso-Pineda et al (2007), OTM and TL values were 6.8 and 67.6 µm, respectively. In our population, only one child had a similar OTM value (7.1).…”

Section: Resultsmentioning

confidence: 91%

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Biomonitoring of a Population Residing Near to Mine Tailings in Guanajuato, Mexico

Salazar

Amador

Vera

et al. 2020

RICA

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Some metals present in residues coming from mining activities can damage DNA. A preliminary evaluation was carried out to determine the genotoxic effects on a resident population from a mining area in Xichú, Guanajuato, Mexico. Blood lead levels (BLL), and arsenic levels in urine (AsU), were measured as biomarkers of exposure. Hematological damage was evaluated trough hematocrit, hemoglobin and activity of enzyme delta-aminolevulinic dehydratase (δ-ALAD). DNA damage in blood cells was evaluated by comet assay. BLL (7.5 ± 1.2 and 7.9 ± 3.3 μg/dL) and AsU (25.2 ± 15.8 and 18.3 ± 18.4 μg/g creatinine) were found in children and adults, respectively. Of the children and adults, 100 and 91.7 %, respectively had levels of enzyme activity below 20 U/L erythrocytes. Regarding DNA damage, the children showed an Olive tail moment of 5.0 ± 1.6 and a tail length of 40.9 ± 4.9 μm, of similar magnitude than adults (4.6 ± 1.0 and 41.8 ± 5.9 μm, respectively). In conclusion, this preliminary study describes the health risk scenario of population near the mine, nevertheless, more studies are needed in the area.Palabras clave: plomo, arsénico, genotoxicidad, jales mineros RESUMEN Algunos metales presentes en residuos provenientes de actividades mineras pueden dañar al ADN. Se llevó a cabo una evaluación preliminar para determinar efectos genotóxicos en población residente de un área minera en Xichú, Guanajuato, México. Los niveles de plomo en sangre (PbS) y los niveles de Arsénico en orina (AsO) fueron

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Section: Resultssupporting

confidence: 70%

Section: Resultsmentioning

confidence: 91%