An integrated biorefinery process: Stepwise extraction of fucoxanthin, eicosapentaenoic acid and chrysolaminarin from the same Phaeodactylum tricornutum biomass

Zhang, Wenyuan; Wang, Feifei; Gao, Baoyan; Huang, Luodong; Zhang, Chengwu

doi:10.1016/j.algal.2018.04.002

Cited by 81 publications

(53 citation statements)

References 44 publications

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“…Green microalgae like Chlorella vulgaris are well‐known for a high protein content and their capability to accumulate high amounts of triacylglycerides (TAG) with mainly monounsaturated fatty acids (Ursu et al, ). In contrast, diatoms like Phaeodactylum tricornutum can provide a high amount of polyunsaturated fatty acids (PUFA), for example, eicosapentaenoic acid (EPA, 20:5 ω‐3) as well as carotenoids (Gille, Trautmann, Posten, & Briviba, ; Ryckebosch et al, ; Zhang, Wang, Gao, Huang, & Zhang, ).…”

Section: Introductionmentioning

confidence: 99%

Pressurized extraction of unsaturated fatty acids and carotenoids from wet Chlorella vulgaris and Phaeodactylum tricornutum biomass using subcritical liquids

et al. 2018

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The objective of this study was to investigate the extraction of lipids, for example, mono‐ and polyunsaturated fatty acids (PUFA) as well as carotenoids, from wet microalgae biomass using pressurized subcritical extraction solvents, which meet the requirements of food and feed applications. To demonstrate the effect of the solvent and temperature on the lipid yield, we chose two microalgae species, viz. Chlorella vulgaris and Phaeodactylum tricornutum, differing in their biochemical composition fundamentally. In case of P. tricornutum, ethanol showed the highest fatty acid yield of 85.9% w/w. In addition to eicosapentaenoic acid (EPA), the ethanolic extracts contained exceptional amounts of fucoxanthin (up to 26.1 mg/g d. w.), which can be beneficial to protect unsaturated fatty acids from oxidation processes and in terms of human nutrition. For C. vulgaris, a fatty acid yield of 76.5% w/w was achieved from wet biomass using ethyl acetate at 150°C. In general, an increase in the extraction temperature up to 150°C was found to be important in terms of fatty acid yield when extracting wet microalgae biomass. The results suggest that it is possible to efficiently extract both fatty acids and carotenoids from wet microalgae by selecting suitable solvents and thus circumvent energy‐intensive drying of the biomass.

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Section: Introductionmentioning

confidence: 99%

Pressurized extraction of unsaturated fatty acids and carotenoids from wet Chlorella vulgaris and Phaeodactylum tricornutum biomass using subcritical liquids

et al. 2018

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“…Biohydrogen [120] Omega-3 rich oil Proteins [121] Lipids pigments Biohydrogen [122] Spirulina spp. Proteins Biomethane and biocrude oil [123] Phycocyanin Chlorophylls [124] Dunaliella tertiolecta Lipids Carbohydrates Bio-oils [125,126] Phaeodactylum tricornutum Fucoxanthin EPA then chrysolaminarin [11] Isochrysis galbana Carotenoids Nonpolar lipids Carotenoids, chlorophylls, mid to highlypolar lipids then proteins and sugars [16] 4.1. Co-Extraction of Multiple Compounds from Marine Microalgae…”

Section: Biofuelmentioning

confidence: 99%

“…Separation of high-value carotenoids requires numerous chromatographic techniques or optimization of solvent polarity using solvent mixtures. It was reported that fucoxanthin and EPA could be purified and concentrated from P. tricornutum through a series of extraction and separation processes [11]. In addition, a two-phase system was proposed to separate the biodiesel from free lutein [15].…”

Section: Co-extraction Of Multiple Compounds From Marine Microalgae Bmentioning

confidence: 99%

“…Hence, the comprehensive utilization of marine microalgae by using most components of biomass for the co-production of multiple compounds instead of sole products can be an efficient way to reduce the production cost of bioactive compounds and improve production efficiency. This includes enhancing the production and biorefinery abilities to obtain multiple compounds from marine microalgae [10,11].…”

Section: Introductionmentioning

confidence: 99%

“…Some compounds (such as fatty acid and lutein) can be simultaneously extracted from microalgal biomass, due to the similar physicochemical properties, such as polarity, hydrophobicity, solubility, and molecular weight [15]. Additionally, stepwise extraction of lipids, pigments, carbohydrates, and proteins from biomass has been performed in marine microalgae [11,16]. Previous studies mainly targeted single product, and microalgal residues were not completely used; but rather were discarded as wastes, which were still rich in valuable compounds [17,18].…”

Section: Introductionmentioning

confidence: 99%

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Comprehensive Utilization of Marine Microalgae for Enhanced Co-Production of Multiple Compounds

Wang

Chua

et al. 2020

Marine Drugs

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Marine microalgae are regarded as potential feedstock because of their multiple valuable compounds, including lipids, pigments, carbohydrates, and proteins. Some of these compounds exhibit attractive bioactivities, such as carotenoids, ω-3 polyunsaturated fatty acids, polysaccharides, and peptides. However, the production cost of bioactive compounds is quite high, due to the low contents in marine microalgae. Comprehensive utilization of marine microalgae for multiple compounds production instead of the sole product can be an efficient way to increase the economic feasibility of bioactive compounds production and improve the production efficiency. This paper discusses the metabolic network of marine microalgal compounds, and indicates their interaction in biosynthesis pathways. Furthermore, potential applications of co-production of multiple compounds under various cultivation conditions by shifting metabolic flux are discussed, and cultivation strategies based on environmental and/or nutrient conditions are proposed to improve the co-production. Moreover, biorefinery techniques for the integral use of microalgal biomass are summarized. These techniques include the co-extraction of multiple bioactive compounds from marine microalgae by conventional methods, super/subcritical fluids, and ionic liquids, as well as direct utilization and biochemical or thermochemical conversion of microalgal residues. Overall, this review sheds light on the potential of the comprehensive utilization of marine microalgae for improving bioeconomy in practical industrial application.

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Algal Derived Functional Lipids and their Role in Promoting Health

Terme

Chénais

Fournière

et al. 2021

Recent Advances in Micro and Macroalgal Processing

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Algae are organisms with an enormous biodiversity and contain manifold fatty acid molecular structures and ratios. This chapter presents information about the structure and distribution of fatty acids in algae whether microalgae or macroalgae. The parameters affecting lipid and fatty acid contents as well as distribution are also discussed. Methods for isolation and purification of fatty acids from algae to obtain highly pure fatty acid or fatty acid fractions with good overall yields are presented. Algal fatty acids are known as sources of bioactive compounds for health promotion and wellness. Lipid fractions and fatty acids act as actives or additives for cosmeceutical applications. For health promotion, preventive effects of n-3 polyunsaturated fatty acids on cardiovascular disease, metabolic syndrome and cancer are discussed. The role of n-3 fatty acids in cancer therapy and antiviral activities of lipids are also exposed. Furthermore, potential commercial application domains and concepts are discussed in this chapter.

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An integrated biorefinery process: Stepwise extraction of fucoxanthin, eicosapentaenoic acid and chrysolaminarin from the same Phaeodactylum tricornutum biomass

Cited by 81 publications

References 44 publications

Pressurized extraction of unsaturated fatty acids and carotenoids from wet Chlorella vulgaris and Phaeodactylum tricornutum biomass using subcritical liquids

Pressurized extraction of unsaturated fatty acids and carotenoids from wet Chlorella vulgaris and Phaeodactylum tricornutum biomass using subcritical liquids

Comprehensive Utilization of Marine Microalgae for Enhanced Co-Production of Multiple Compounds

Algal Derived Functional Lipids and their Role in Promoting Health

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