An integrated bioinformatics approach to identify key biomarkers in the tubulointerstitium of patients with focal segmental glomerulosclerosis and construction of mRNA–miRNA-lncRNA/circRNA networks
Yun Xia Zhang,
Jun Yuan Bai,
XiaoWei Pu
et al.
Abstract:Objective
The purpose of this study was to identify potential biomarkers in the tubulointerstitium of focal segmental glomerulosclerosis (FSGS) and comprehensively analyze its mRNA–miRNA-lncRNA/circRNA network.
Methods
The expression data (GSE108112 and GSE200818) were downloaded from the Gene Expression Omnibus database (
https://www.ncbi.nlm.nih.gov/geo/
). Identification and enrichment analysis of differentially expressed genes (DEGs) were … Show more
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