Issues of spirituality and religion are seldom discussed in the globalization context. Spirituality and religion affect the globalization phenomenon and are, in turn, significantly influenced by globalization. This article explores the interplay between spirituality and religion, and the forces of economics, technology, and globalization. Contemporary globalization exhibits five main trends in spirituality and religion: increasing attempts to harness religion and spirituality as means toward reterritorialization, the integration of spirituality in all aspects of life, a greater thrust toward the individualization of spirituality among consumers, the enhanced role of cyberspace in the spiritual domain, and the syncretization of spirituality. These five trends affect quality of life as well as the relationship between governments and markets, two areas of interest to macromarketers.