An instrument for measuring blood pressure and assessing cardiovascular health from the fingertip

Panula, Tuukka; Koivisto, Tero; Pänkäälä, Mikko; Niiranen, Teemu J.; Kantola, Ilkka; Kaisti, Matti

doi:10.1016/j.bios.2020.112483

Cited by 33 publications

(33 citation statements)

References 38 publications

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“…An arbitrary validation protocol (n=33) comparing the device to an automated arm cuff monitor yielded results of (−0.9 ± 7.3) mmHg and (−3.3 ± 6.6) mmHg for SBP and DBP, respectively. [79] D. Pulse propagation methods BP estimation using PTT or PAT has been adopted by many companies and there have been efforts to measure absolute BP via PTT/PAT. However, it seems that it is best used for assessing relative changes in calibrated BP rather than used in spot BP measurements.…”

Section: Tonometrymentioning

confidence: 99%

“…SOMNOmedics' SOMNOtouch uses a similar approach [49]. j) Developed at University of Turku, FANTOM is a finger-worn device that uses tonometry combined with oscillometry for measuring BP and recording arterial waveform [79]. k) Healthstats BPro is a smartwatch-type device with a tonometric plunger that records radial artery waveform and in order to measure continuous BP [72].…”

Section: B Machine Learningmentioning

confidence: 99%

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Advances in Non-Invasive Blood Pressure Measurement Techniques

Panula

Sirkiä

Wong

et al. 2023

IEEE Rev. Biomed. Eng.

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Hypertension, or elevated blood pressure (BP), is a marker for many cardiovascular diseases and can lead to life threatening conditions such as heart failure, coronary artery disease and stroke. Several techniques have recently been proposed and investigated for non-invasive BP monitoring. The increasing desire for telemonitoring solutions that allow patients to manage their own conditions from home has accelerated the development of new BP monitoring techniques. In this review, we present the recent progress in non-invasive blood pressure monitoring solutions emphasizing clinical validation and trade-offs between available techniques. We introduce the current BP measurement techniques with their underlying operating principles. New promising proof-ofconcept studies are presented and recent modeling and machine learning approaches for improved BP estimation are summarized. This aids discussions on how new BP monitors should evaluated in order to bring forth new home monitoring solutions in wearable form factor. Finally, we discuss on unresolved challenges in making convenient, reliable and validated BP monitoring solutions.

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Section: Tonometrymentioning

confidence: 99%

Section: B Machine Learningmentioning

confidence: 99%

Advances in Non-Invasive Blood Pressure Measurement Techniques

Panula

Sirkiä

Wong

et al. 2023

IEEE Rev. Biomed. Eng.

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“…However, this approach is not very accurate, and does not provide adequate precision [16]. Most of the techniques based on this approach employ a wrapped cuff around an extremity (commonly the arm), which is then inflated, resulting in blood flow occlusion [24]. After this, the cuff pressure is reduced, thereby allowing the return of arterial blood flow.…”

Section: ) Non-invasive Techniquementioning

confidence: 99%

Modeling of On-Chip Biosensor for the in Vivo Diagnosis of Hypertension in Wireless Body Area Networks

et al. 2021

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High Blood Pressure (HBP) over a long period of time leads to a medical condition known as Hypertension (HTN or HT), in which the arterial blood pressure is persistently inflated. In this research, a blood pressure biosensor has been implemented that monitors the different stages of hypertension by measuring the varying blood pressure values. Further, a system design has been proposed for the theranostics (combination of diagnosis and therapy) of hypertension. The proposed sensor takes blood pressure as the input, and gives the corresponding electrical signal variations at the output, so as to detect the exact stage of hypertension. The working principle of this BP sensor is based on the electrostatic transduction mechanism. The proposed system aims to design a low-cost, easily available, implantable lab-on-chip (LoC) platform for the continuous measurement of blood pressure by keeping track of the patient history, so as to prevent chronic hypertensive disorders. Further, such an implantable LoC theranostic platform is among the best possible solutions for the e-healthcare systems, owing to its potential in a wireless body area network (WBAN) using Internet of Things (IoT) and other similar technologies.

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“…Even though the effects of skin tone and pigmentation are non-negligible [ 13 , 14 ], optical sensors are suitable for miniaturization because of their simple components; hence, they have been used in commercial smartwatches and pulse oximeters. By contrast, mechanical sensors measure pulse waves by detecting pulse-induced skin deformation above the blood vessel, which typically involves strain or pressure [ 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ]. Mechanical detection provides direct information regarding physical phenomena occurring in the blood vessels.…”

Section: Introductionmentioning

confidence: 99%

Frequency Characteristics of Pulse Wave Sensor Using MEMS Piezoresistive Cantilever Element

2022

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Wearable sensor devices with minimal discomfort to the wearer have been widely developed to realize continuous measurements of vital signs (body temperature, blood pressure, respiration rate, and pulse wave) in many applications across various fields, such as healthcare and sports. Among them, microelectromechanical systems (MEMS)-based differential pressure sensors have garnered attention as a tool for measuring pulse waves with weak skin tightening. Using a MEMS-based piezoresistive cantilever with an air chamber as the pressure change sensor enables highly sensitive pulse-wave measurements to be achieved. Furthermore, the initial static pressure when attaching the sensor to the skin is physically excluded because of air leakage around the cantilever, which serves as a high-pass filter. However, if the frequency characteristics of this mechanical high-pass filter are not appropriately designed, then the essential information of the pulse-wave measurement may not be reflected. In this study, the frequency characteristics of a sensor structure is derived theoretically based on the air leakage rate and chamber size. Subsequently, a pulse wave sensor with a MEMS piezoresistive cantilever element, two air chambers, and a skin-contacted membrane is designed and fabricated. The developed sensor is 30 mm in diameter and 8 mm in thickness and realizes high-pass filter characteristics of 0.7 Hz. Finally, pulse wave measurement at the neck of a participant is demonstrated using the developed sensor. It is confirmed that the measured pulse wave contains signals in the designed frequency band.

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An instrument for measuring blood pressure and assessing cardiovascular health from the fingertip

Cited by 33 publications

References 38 publications

Advances in Non-Invasive Blood Pressure Measurement Techniques

Advances in Non-Invasive Blood Pressure Measurement Techniques

Modeling of On-Chip Biosensor for the in Vivo Diagnosis of Hypertension in Wireless Body Area Networks

Frequency Characteristics of Pulse Wave Sensor Using MEMS Piezoresistive Cantilever Element

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