An insight on nanofibers assisted localized delivery of anti-cancer drugs to breast for an effective breast cancer treatment

Chaturvedi, Shashank; Rastogi, Vaibhav; Kumar, Mukesh

doi:10.1016/j.jddst.2024.105447

Journal of Drug Delivery Science and Technology

2024

DOI: 10.1016/j.jddst.2024.105447

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An insight on nanofibers assisted localized delivery of anti-cancer drugs to breast for an effective breast cancer treatment

Shashank Chaturvedi,

Vaibhav Rastogi,

Mukesh Kumar

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2024

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Cited by 1 publication

References 187 publications

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One‐Step DES‐Mediated Synthesis of Au Nanoparticles Using Eysenhardtia polystachya Extract and Evaluation of Their Proapoptotic and Anti‐Inflammatory Activities

Gutiérrez‐Sánchez,

Molina,

López‐Miranda

et al. 2024

ChemistrySelect

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The synthesis of nanomaterials using plant extracts is considered to be a safer, environmentally friendly, and cost‐effective alternative method. In this work, Eysenhardtia polystachya (EP) extract and choline chloride/urea (ChCl/urea)‐based deep eutectic solvent (DES) were used for the synthesis of gold nanoparticles (AuNPs), without an additional stabilizing agent, which is of great interest in the field of biomedicine. The antioxidant capacity of the extract and the phenolic content, involved in the reduction of Au3+ ions of the precursor were evaluated. The AuNPs were characterized by ultraviolet‐visible spectroscopy, Fourier transform infrared spectroscopy, X‐ray diffraction, dynamic light scattering, ζ‐potential, confocal laser scanning microscopy, scanning and transmission electron microscopy. The nanoparticles are mostly quasi‐spherical shape, with a multiply‐twinned structure, an average particle size of 36 nm, and a characteristic absorption peak at 545 nm. The colloidal stability was confirmed with a ζ‐potential value of −32.8 mV. Finally, the AuNPs were tested for their potential in cancer therapy using human prostate adenocarcinoma PC‐3 cells. The anti‐inflammatory activity of the EP extract and AuNPs was also evaluated. The results showed that the synthesized AuNPs could potentially induce cell death and have an anti‐inflammatory effect.

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One‐Step DES‐Mediated Synthesis of Au Nanoparticles Using Eysenhardtia polystachya Extract and Evaluation of Their Proapoptotic and Anti‐Inflammatory Activities

Gutiérrez‐Sánchez,

Molina,

López‐Miranda

et al. 2024

ChemistrySelect

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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An insight on nanofibers assisted localized delivery of anti-cancer drugs to breast for an effective breast cancer treatment

Cited by 1 publication

References 187 publications

One‐Step DES‐Mediated Synthesis of Au Nanoparticles Using Eysenhardtia polystachya Extract and Evaluation of Their Proapoptotic and Anti‐Inflammatory Activities

One‐Step DES‐Mediated Synthesis of Au Nanoparticles Using Eysenhardtia polystachya Extract and Evaluation of Their Proapoptotic and Anti‐Inflammatory Activities

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