An insight into the gut microbiota after Schistosoma japonicum eggs immunization in an experimental ulcerative colitis model
Peng Wu,
Wenhao Li,
Yiting Xie
et al.
Abstract:Schistosome infection and schistosome‐derived products have been implicated in the prevention and alleviation of inflammatory bowel disease by manipulating the host immune response, whereas the role of gut microbiota in this protective effect remains poorly understood. In this study, we found that the intraperitoneal immunization with Schistosoma japonicum eggs prior to dextran sulfate sodium (DSS) application significantly ameliorated the symptoms of DSS‐induced acute colitis, which was characterized by highe… Show more
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