Lab courses are a significant component of biochemistry and molecular biology (BMB) education. In teaching the labs, we combine established techniques with novel approaches. Lab formats have also moved from traditional cookbook style labs to guided inquiry to course-based undergraduate research experiences (CUREs), where faculty bring their own research interests into the course setting with a larger number of students in a much more restricted time frame. This presentation is designed to explore some of these ideas and challenge the reader to introduce research opportunities to all students, not just the smaller group of students in their research labs. K E Y W O R D S computational biology, computers in research and teaching, enzymes and catalysis, genomics proteomics bioinformatics, integration of research into undergraduate teaching, laboratory exercises, molecular visualization, new course development