An Initial Investigation of the Joint Classification of Hypomania- and Neurodevelopmental Disorder-Relevant Dimensions within the Hierarchical Taxonomy of Psychopathology

Abstract

We present results from samples of online community adults screened based on psychopathology history (N = 429) and undergraduates (N = 529) informing classification of neurodevelopmental disorder (NDD)- and hypomania-relevant dimensions within the Hierarchical Taxonomy of Psychopathology (HiTOP). Our results advance prior research focused primarily on analyses of diagnostic composite ratings by indicating that distinct NDD- and mania-relevant traits align closely with different HiTOP spectra. For instance, hypomania-relevant dimensions such as self-perceived creativity aligned with thought disorder, whereas other hypomania dimensions reflected internalizing. Additionally, factors identified showed distinctive associations cross-sectionally and prospectively using data from a 2-week follow-up assessment completed by most online community participants (N = 377). For example, a hypomania/thought disorder factor showing meaningful associations with later hypomanic symptoms after accounting for initial symptoms. We discuss how these results inform HiTOP assessment efforts, as well as future directions for sharpening our understanding of classifying NDD- and hypomania-relevant dimensions.

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“…Participants were screened based on a history of mental health issues using the same filter described previously. These data were collected as part of a broader study focused on improving transdiagnostic mental health assessment (see Stanton et al, 2021). All analyses presented are original, and more information regarding this study's goals and data exclusions (i.e., scores from measures that were administered but not included here) are provided in Online Appendix S1.…”