An Inexpensive Protocol for Biginelli Reaction

CF3-substituted 1,3-dicarbonyl compounds in the Biginelli reaction promoted by chlorotrimethylsilane

“…19 2, 128.5, 128.6, 128.7, 128.9, 133.7, 137.8, 138.8, 154.3, 196.3 2, 128.56, 128.59, 128.77, 128.83, 133.5, 137.7, 138.0, 155.7, 195.7. 19 ,4.53;F,15.06;N,7.40;O,12.69. Found: C,60.39;H,4.45;N,5R, ,4.34;F,14.45;N,7.10;O,8.11;S,8.13.…”

Heterogeneous liquid phase synthesis of 3,4-dihydropyrimidine-2(1H)-ones using aluminated mesoporous silica

“…Many Lewis acids such as Cu(OTf) 2 , CuCl 2 , Ag 3 PW 12 O 40 , FeCl 3 ⋅6H 2 O, Me 3 SiCl [6][7][8][9][10], and protic acids such as NH 2 SO 3 H, NH 4 Cl [11,12] were employed for this reaction. Other special methods including ionic liquids, microwave irradiation, trimethylsilyl-triflate, polyaniline-bismoclite complex, L-proline, grindstone chemistry, and I 2 were also employed [13][14][15] for this transformation, but all these processes suffer from many drawbacks such as purification of the product, the reaction yield and the use of hazardous organic synthesis.…”

Three-Component One-Pot Synthesis of Novel Benzo[b]1,8-naphthyridines Catalyzed by Bismuth(III) Chloride

“…The utility of different metal salts such as mercuric salts, lead salts, zinc chloride, cadmium chloride, and indium chloride, lanthanide compounds, InBr 3 , ZrCl 4 [12,13], as potential catalyst in variety of synthetic reactions was recognized in recent years. However, the expensiveness and toxicity of some metal salts hampers their wide applications in organic synthesis.…”