An industrialized diet as a determinant of methylation in the 1F region of the NR3C1 gene promoter
Tamires dos Santos Vieira,
Flávia Vitorino Freitas,
Luiz Cláudio Barreto Silva Neto
et al.
Abstract:BackgroundDietary composition can modify gene expression, favoring the development of chronic diseases via epigenetic mechanisms.ObjectiveOur study aimed to investigate the relationship between dietary patterns and NR3C1 gene methylation in users of the Brazilian Public Unified Health System (SUS).MethodsWe recruited 250 adult volunteers and evaluated their socioeconomic status, psychosocial characteristics, lifestyle, and anthropometrics. Peripheral blood was collected and evaluated for cortisol levels, glyce… Show more
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