An increased carbon dioxide production in transient hypoxia in healthy subjects at rest

Grishin, O. V.; Basalaeva, S. V.; Уманцева, Н. Д.; Ustyuzhaninova, N. V.; Grishin, V. G.; Митрофанов, И. М.

doi:10.1134/s0362119711040086

Hum Physiol

2011

DOI: 10.1134/s0362119711040086

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An increased carbon dioxide production in transient hypoxia in healthy subjects at rest

O. V. Grishin

S. V. Basalaeva

Н. Д. Уманцева

et al.

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Cited by 3 publications

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“…Laboratory studies more often use short term nor mobaric hypoxic exposures with sharp decreases in the oxygen concentration (to 10-12%) of the inspired gas mixture [3][4][5][6]. This practice helped acquire experience in the application of brief intermittent hypoxic expo sures for preacclimatization in preparation for high altitude ascents [7] or improving sports results [7][8][9][10], as well as for the prevention and treatment of cardiovas cular and respiratory diseases [11,12].…”

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Cardiorespiratory responses to prolonged normobaric inhalatory hypoxia in healthy men

Диверт

Кривощеков

2013

Hum Physiol

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Changes in the cardiorespiratory indicators due to the prolonged (25 min) inhalation of a respira tory mixture with an exponentially falling (from 20.9% to 10%) oxygen concentration were studied in healthy young men. The efficiency of oxygen uptake (as the ventilatory equivalent of O 2 ) in the lungs has been shown to fall particularly promptly (within the first 2-5 min). Individual manifestations of this fall were variable (ranging from 22 to 84% of the baseline data) and driven, to a considerable degree, by the subject's current level of alveolar ventilation, mobilizing its urgent reserve to improve the ventilation-perfusion relations in the lungs. The subsequent response as a growth in the heart rate (HR) recorded in 100% of cases was delayed rel ative to the start of hypoxic exposure and combined with increased hypoxemia marked as a decrease in the blood oxygen saturation of hemoglobin. The individual HR growth in response to hypoxia ranged from 8 to 43% of the baseline level and was significantly related to the current level of diastolic arterial blood pressure. The hypoxic ventilatory response was expressed only in 71% of cases, including the 15% when it was reversed (decreased) against the background of a concomitant decrease in the respiratory frequency.

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confidence: 99%

Cardiorespiratory responses to prolonged normobaric inhalatory hypoxia in healthy men

Диверт

Кривощеков

2013

Hum Physiol

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Changes in pulmonary gas exchange during resistive loading that do not cause a sense of shortness of breath

2014

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Clinical use of pulse oximetry in adults

Grishin

2020

Medicinskij alfavit

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The article is devoted to the practical aspects of pulse oximetry. Pulse oximetry is a photoplethysmographic method for determining heart rate and the percentage of oxyhemoglobin in arterial blood. The method allows you to objectively evaluate arterial hypoxemia, therefore, it can be used in functional diagnostics and in the daily practice of interns of any specialization. The article briefly presents the history of pulse oximetry and a description of the technique. Particular attention is paid to the accuracy of measurements and reference values of pulse oximetry. The functional significance ofpulse oximetry is also considered here. Several sections are devoted to practical issues: interpretation of the results of pulse oximetry in the diagnosis of arterial hypoxia, in the differential diagnosis of shortness of breath, the diagnostic value of the phenomenon of desaturation. A large section is devoted to the importance of pulse oximetry in viral pneumonia COVID-19

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An increased carbon dioxide production in transient hypoxia in healthy subjects at rest

Cited by 3 publications

References 9 publications

Cardiorespiratory responses to prolonged normobaric inhalatory hypoxia in healthy men

Cardiorespiratory responses to prolonged normobaric inhalatory hypoxia in healthy men

Changes in pulmonary gas exchange during resistive loading that do not cause a sense of shortness of breath

Clinical use of pulse oximetry in adults

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