An in vivo study of the effect of excimer laser irradiation on degenerate rabbit articular cartilage

Efficacy of different therapy regimes of low‐power laser in painful osteoarthritis of the knee: A double‐blind and randomized‐controlled trial

“…Bassleer et al [37] concluded that LPLT also has cartilage stimulatory properties in humans. Proteoglycan synthesis, quantified by radioimmunoassay, was significantly increased using an infrared laser (904 nm) [38]. LPLT may possibly be through its positive effects on chondrocyte proliferation and matrix synthesis [31,38,39].…”

Effects of neuromuscular electrical stimulation and low-level laser therapy on the muscle architecture and functional capacity in elderly patients with knee osteoarthritis: a randomized controlled trial

“…Despite the body of evidence on the positive effects of low-level laser therapy on cartilage, 20,21 a placebo effect might have contributed to the patients’ improved performance on the 6-minute walk test. As an investigation of the real analgesic, 19 anti-inflammatory 11 and regenerative 20,21 effects on cartilage is beyond the focus of the present study, future studies could use magnetic resonance imaging to evaluate the effect of low-level laser therapy on cartilage structure and inflammatory markers in osteoarthritic patients, and to assess the correlation of these effects with the clinical findings of improved functionality.…”

Advances in the microscopy of osteoarthritis

“…In rabbit OA initiated mechanically, irradiation of the degenerate articular surface by xenon chloride ultraviolet 308 nm laser is followed by macroscopic and microscopic evidence of smoothing of the degenerate surfaces. The effects appeared to be transient (Reed et al, 1994).…”