An in-vitro toxicity testing - a reliable alternative to toxicity testing by reduction, replacement and refinement of animals.

Bhanushali, Mittal M; Bagale, V.; Shirode, Abhay; Joshi, Yadunath M.; Kadam, Vivek

doi:10.5138/ijaps.2010.0976.1055.01002

Cited by 9 publications

(5 citation statements)

References 60 publications

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“…In the last few years, several in vitro toxicity assays have been developed and validated in order to replace animal testing methods (Bhanushali, Bagale, Shirode, Joshi, & Kadam, 2010). Regarding Lavandula essential oil's toxicity very few studies are known.…”

Section: Discussionmentioning

confidence: 99%

Lavandula luisieri essential oil as a source of antifungal drugs

et al. 2012

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Section: Discussionmentioning

confidence: 99%

Lavandula luisieri essential oil as a source of antifungal drugs

et al. 2012

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“…These alternative methods have been developed and validated using the Reduction, Replacement and Refinement (3Rs) approach. One of the most commonly used approaches for in vitro cytotoxicity assessment utilizes various continuous cell lines [15]. The presented study was designed to define the cytotoxicity of fractions obtained from flowers of Alnus sieboldiana.…”

Section: Discussionmentioning

confidence: 99%

In vitro evaluation of cytotoxicity of n-hexane extract from Alnus sieboldiana male flowers on VERO and HEK293 cell lines

Świątek

Rajtar

Pawlak

et al. 2014

J Pre Clin Clin Res.

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“…In Indian girls, the highest prevalence of anaemia is reported between the ages of 12-13 years which also coincides with the average age of menarche. In girls, the lower total food intake or energy intake by compared to boys, combined with menstrual losses cause adolescent girls to be at greater risk of Iron deficiency and IDA [4] . The study result showed that prevalence of anemia was found to be 35.1%.…”

Section: Populationmentioning

confidence: 99%

Iron deficiency anaemia and effect of nutrition education on change in dietary behavior among the adolescent girls of tea garden area in Nagaon District, Assam

Bhagya¹,

Dipak²

2023

Int. J. Res. Paediatric Nurs.

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Anaemia is a manifestation of under-nutrition and poor dietary intake of iron is a serious public Health problem among pregnant woman, infants, young children and adolescents. The prevalence the prevalence of Anaemia is high in developing countries than the developed countries due to poverty, inadequate diet, high incidence of communicable diseases, Pregnancy /lactation and low immunity. India has the highest prevalence of Anaemia among women, including adolescent, worldwide. Between 60 to 70% of Indian adolescent girls are anemic (Hemoglobin (Hb) <12g/dl). Therefore, to address this strategic gap, the researcher would like to conduct a participatory nutrition education and intervention on Iron rich diet study to improve the dietary behavior status, and reduce the prevalence of anemia among unmarried adolescent girls 1 .The main objective of the study was to assess the haemoglobin level among adolescent girls before nutrition education on Iron rich food. To assess the dietary practices among the adolescent tea garden Girls in selected Tea Garden of Nagaon District, Assam and to find out the effectiveness of Nutrition education on changing dietary practices among the adolescent girls of Tea Garden, Nagaon District Assam The research approach is Descriptive Evaluative approach and Research design adopted was pre-experimental one group pre-test post-test design. The total sample for the study is 800. Hence the for the Present pilot study the Researches has collected the Data from 10% of the total Population i.e. 80 numbers of Adolescent girls of Lungsung and Chapanala Tea Garden area of Nagaon District. The study results shows that food consumption habit mean score in Baseline assessment is higher than the Endline assessment Paired 't' value is 31.54 which was significant at p<0.05 level. There is significant association between the pretest level of Hb with the selected Demographic Variable such as age, religion, working status, water sanitation, consumption of Iron Tablets and Consumption of Albendazole tablet. As the tabulated value is less than the calculated value of Chi-square at p<0.05 level.

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An in-vitro toxicity testing - a reliable alternative to toxicity testing by reduction, replacement and refinement of animals.

Cited by 9 publications

References 60 publications

Lavandula luisieri essential oil as a source of antifungal drugs

Lavandula luisieri essential oil as a source of antifungal drugs

In vitro evaluation of cytotoxicity of n-hexane extract from Alnus sieboldiana male flowers on VERO and HEK293 cell lines

Iron deficiency anaemia and effect of nutrition education on change in dietary behavior among the adolescent girls of tea garden area in Nagaon District, Assam

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