An in vitro study on antimicrobial and anticancer potentiality of thyme and clove oils

El-Darier, Salama M.; ElAhwany, Amani M. D.; El-Kenany, Eman T.; Abdeldaim, Ahmed A.

doi:10.1007/s12210-018-0672-0

Cited by 22 publications

(7 citation statements)

References 33 publications

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“…The antibacterial mechanism has been related to the -OH groups located at the meta and ortho positions, respectively, in the main chemical composition. These functional groups can interact with the cytoplasmic membrane of microbial cells [92,96,97,99,100]. CEO can permeate through the cell membrane due to its lipophilic properties.…”

Section: Antimicrobialmentioning

confidence: 99%

“…The interaction of CEO with polysaccharides, fatty acids, and phospholipids causes loss of cellular membrane integrity, leakage of cellular contents, and interference with proton pump activity, leading to cell death [92,96,97,100,110]. CEO can inhibit Gram-negative bacteria (E. coli, Salmonella, Klebsiella pneumoniae, Erwinia carotovora, Agrobacterium, and Pseudomonas aeruginosa) and Gram-positive bacteria (S. aureus, Streptococcus, and L. monocytogenes), Aspergillus (A. flavus, A. parasiticus, and A. ochraceus), Penicillium, C. albicans, and yeast [92,96,97,100]. CEO inhibits Gram-positive bacteria to a greater extent than Gram-negative bacteria.…”

Section: Antimicrobialmentioning

confidence: 99%

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Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

et al. 2021

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Clove (Syzygium aromaticum L. Myrtaceae) is an aromatic plant widely cultivated in tropical and subtropical countries, rich in volatile compounds and antioxidants such as eugenol, β-caryophyllene, and α-humulene. Clove essential oil has received considerable interest due to its wide application in the perfume, cosmetic, health, medical, flavoring, and food industries. Clove essential oil has biological activity relevant to human health, including antimicrobial, antioxidant, and insecticidal activity. The impacts of the extraction method (hydrodistillation, steam distillation, ultrasound-assisted extraction, microwave-assisted extraction, cold pressing, and supercritical fluid extraction) on the concentration of the main volatile compounds in clove essential oil and organic clove extracts are shown. Eugenol is the major compound, accounting for at least 50%. The remaining 10–40% consists of eugenyl acetate, β-caryophyllene, and α-humulene. The main biological activities reported are summarized. Furthermore, the main applications in clove essential oil in the food industry are presented. This review presents new biological applications beneficial for human health, such as anti-inflammatory, analgesic, anesthetic, antinociceptive, and anticancer activity. This review aims to describe the effects of different methods of extracting clove essential oil on its chemical composition and food applications and the biological activities of interest to human health.

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Section: Antimicrobialmentioning

confidence: 99%

Section: Antimicrobialmentioning

confidence: 99%

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

et al. 2021

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“…The antibacterial mechanism of the CEO has been related to the -OH groups located at the meta and ortho positions in the CEO main chemical composition, respectively. These functional groups can interact with the cytoplasmic membrane of microbial cells [82,86,87,89,90]. The CEO is permeable through the cell membrane due to its lipophilic properties.…”

Section: Antimicrobialmentioning

confidence: 99%

“…The interaction of CEO with polysaccharides, fatty acids, and phospholipids causes loss of cellular membrane integrity, leakage of cellular contents, interference in proton pump activity, and conducts to cell death [82,86,87,90,100]. The CEO can inhibit Gram-negative bacteria like (E. coli, Salmonella, K. pneumoniae, E. carotovora, Agrobacterium, and P. aeruginosa) and Gram-positive bacteria as (S. aureus, Streptococcus, and L. monocytogenes), Aspergillus (A. flavus, A. parasiticus, and A. ochraceus), Penicillium, C. albicans , and yeast [82,86,87,90]. The CEO inhibited Gram-positive bacteria to a greater extent than Gram-negative bacteria.…”

Section: Antimicrobialmentioning

confidence: 99%

Clove Essential Oil (<em>Syzygium aromaticum L. Myrtaceae</em>): Extraction, Chemical Composition, Food Applications and Essential Bioactivities for Human Health

Haro-González¹,

Castillo-Herrera²,

Martínez-Velázquez³

et al. 2021

Preprint

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Clove (Syzygium aromaticum L. Myrtaceae) is an aromatic plant widely cultivated in tropical and subtropical countries, rich in volatile compounds and antioxidants such as eugenol, β-caryophyllene, and α-humulene. Clove essential oil has received considerable interest due to its wide application in the perfumery, cosmetic, health, medical, flavoring, and food industries. Clove essential oil has relevant biological activities to human health, including antimicrobial, antioxidant, and insecticide. This review describes the effect of the extraction method (hydrodistillation, steam distillation, ultrasound-assisted extraction, microwave-assisted extraction, cold pressing, and supercritical fluid extraction) on the chemical composition of essential oil and its correlation with their biological activities. Likewise, are summarized the main compounds and their reported biological activities. Furthermore, the main applications in clove essential oil in the food industry are presented. Finally, this review presents the new biological activities such as anti-inflammatory, analgesic, anesthetic, antinociceptive and anticancer, which are beneficial for human health. This review aims to compile the effect of different methods of extracting clove essential oil on chemical composition, food applications, as well as a current description of biological activities of interest to human health. Biological activities have increased interest in research into this essential oil and its future applications in the food or pharmaceutical industry.

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“…Essential oils of clove buds (EO-JC) are of particular interest because of their biological activities [15,16]. EO-JC has broad medicinal properties and applications among other uses, as anticancer, antibacterial, antifungal, analgesic, antiseptic, antidiabetic, antiobesity, anti-inflammatory, antioxidant, antiviral, and aphrodisiac [17][18][19][20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Evaluation of Antifungal and Insecticidal Activities of Essential Oils Extracted from Jambosa caryophyllus (Thunb.) Nied: Clove Buds

Zouirech

Alajmi

jeddab

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Jambosa caryophyllus has been used in traditional phytotherapy as a treatment against infections. In the present work, essential oils extracted from clove buds (Jambosa caryophyllus ) (EO-JC) were investigated for their composition, antifungal, and insecticidal properties. Extraction of EO-JC was performed by use of hydrodistillation using a Clevenger-type apparatus, and the EOs were analyzed by gas chromatography coupled with mass spectrometry (GC-MS). Antifungal activity of EO-JC was evaluated by the use of solid-state diffusion (disc method) and microdilution to determine the minimum inhibitory concentration (MIC), against three strains of fungus, Aspergillus niger, Aspergillus flavus, and Fusarium oxysporum. Insecticidal activity of EO-JC against the cowpea weevil, Callosobruchus maculatus, was determined to assess utility of EO-JC to control this pest. Several exposures including inhalation and contact were used to determine lethality, as well as the repulsion test was conducted at concentrations of 4, 8, 16, and 32 μL EO-JC. Characterization of EO-JC by GC/MS revealed 34 compounds accounting for 99.98% of the mass of the extract. The predominant compound was eugenol (26.80%) followed by β-caryophyllene (16.03%) and eugenyl acetate (5.83%). The antifungal activity of EO-JC on solid media exhibited inhibitions in the range of 49% to 87%, and MIC was between 3.125 and 7.80 μg EO-JC/mL. Insecticidal activity, as determined by the use of the inhalation test, and expressed as the LD50 and LD95 after 96 hours of exposure was 2.32 and 21.92 μL/L air, respectively. In the contact test, a 96-hour exposure resulted in LD50 and LD95 of 5.51 and 11.05 μL/L of air, respectively. EO-JC exhibited insecticidal activity against fungi and pest chickpea weevil.

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An in vitro study on antimicrobial and anticancer potentiality of thyme and clove oils

Cited by 22 publications

References 33 publications

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

Clove Essential Oil (<em>Syzygium aromaticum L. Myrtaceae</em>): Extraction, Chemical Composition, Food Applications and Essential Bioactivities for Human Health

Chemical Composition and Evaluation of Antifungal and Insecticidal Activities of Essential Oils Extracted from Jambosa caryophyllus (Thunb.) Nied: Clove Buds

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