An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
Fayeza Sadia Laskar,
Md. Nazmul Islam Bappy,
Md. Sowrov Hossain
et al.
Abstract:Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms of the human body. The impact of mutations occurring in the MET gene is demonstrated by their detrimental effects on normal cellular functions. These mutations can change the structure and function of MET leading to different diseases such as lung cancer, neck ca… Show more
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