Abstract:CRY2 is one of the four central proteins of the cell-autonomous molecular clock in mammals. Numerous missense SNPs have been reported in the cry2 gene which results in missense variants of CRY2. These were correlated with diverse metabolic diseases as well as autism spectrum disorders. Thus, we performed in silico analysis of the human CRY2 (hCRY2) protein, assessing the structural stability and interaction of the protein with the FBXL3 and PER2. Multiple computational tools were used in each phase of the anal… Show more
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