An in-depth study of drugs prescribing pattern in the Surgery Department of a Tertiary Care Teaching Institute in Northern India

Kumar, Raj; Kohli, Kamlesh; Sidhu, Darshan Singh; Kaur, Navjot; Chandra, Mala; Garg, Monique

doi:10.5455/2319-2003.ijbcp20140824

Cited by 7 publications

(9 citation statements)

References 2 publications

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“…All patients received an antimicrobial drug at one time or the other. This is similar to Bhansali et al 23 and Kumar R et al 24 study But this is much higher than the other Indian studies which reports the use of AMA in 20% to 67% of the patients only 15,23 . Similar studies abroad indicate a range of 20% to 42% of patients receiving antimicrobial drugs 25 .…”

Section: Discussionsupporting

confidence: 89%

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

Parulekar¹

2020

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Introduction: Surgical site infection (SSI) is the most common post-operative complication and represents a significant burden in terms of patient morbidity and mortality, and cost to health services around the world. Appropriate antibiotic prophylaxis has been shown to be effective in reducing the incidence of surgical site infections as studies suggest that 40-60% of these infections are preventable. Aims: To evaluate and compare the utilization pattern of antimicrobial agents (AMA) in surgical prophylaxis use in preoperative, intraoperative and post-operative wards of different specialities. Settings and Design: It is a cross-sectional observational study conducted patients admitted to surgery, orthopaedics, ENT and gynaecology wards in tertiary teaching care hospital. Methods and Material: The study duration was from November 2016-November 2018 (2 years).The data was collected time to time from all the medical records of the patient. The study protocol was approved by the Institutional Ethics Committee. Statistical Analysis Used: Data was collected and compiled using Microsoft Excel 2010 and then analysed by calculating simple proportions, frequency and percentage of various parameters. Results: Out of 386 patients, it was observed that female patients (55.69%) were more than male (44.60%) patients. The majority of surgical wounds were clean (39.11%) and most common antimicrobial used pre-operatively was metronidazole (29.24%) and in the intraoperative and postoperative period was gentamicin (54.28%). Number of DDD for inj.amoxicillin-clavulanic acid 1.2g was 274.4. Conclusions: After observing the trend of use of antibiotics, there is a clear need for the development of prescribing guidelines and educational initiatives to encourage the appropriate use of antimicrobials in surgical period. Also, there is scope for improving prescribing habits among the fraternity and minimizing incidence of resistance to antimicrobials.

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Section: Discussionsupporting

confidence: 89%

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

Parulekar¹

2020

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“…Hence, the use of an analgesic has almost become compulsory following surgery. The most commonly used analgesic was diclofenac in our study which is consistent with the findings with that of Salman et al [4], Bhansali et al [11], and Kumar et al (80.0%) [9], wherein it was the most commonly prescribed analgesic. However, the use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly diclofenac for the management of post-operative pain, is controversial [17].…”

Section: Arshad Et Alsupporting

confidence: 93%

“…About 35.10% of patients were prescribed antibiotics in our study which is similar to studies done byMandal et al (30%) [18] and Kumar et al (37.89%)[9]. Metronidazole (85.71%), ceftriaxone (66.03%), and amikacin (56.27%) were the most commonly used antibiotics in our study.…”

supporting

confidence: 89%

“…The average number of antibiotics used in our study came out to be 2, which is higher than reported by Kumar et al (1.55) [9] but lower than reported by Bhansali et al (2.95) [11]. The higher number of antibiotics per patient indicates that more and more antibiotics were used for prophylaxis purpose rather than definitive treatment purpose.…”

Section: Arshad Et Alcontrasting

confidence: 69%

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Drug Utilization Study in Post-Operative Patients in the Surgery Ward of a Tertiary Care Teaching Hospital in South India

Arshad

Raghunandan

Chavan

et al. 2018

Asian J Pharm Clin Res

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Objectives: Pharmacotherapy with multiple agents before, during, and after surgery is marked in the present day indoor hospital setting. The main objective of our research is to evaluate the prescribing and drug utilization patterns using the World Health Organization (WHO) indicators in postoperative patients in the surgery ward of Raichur Institute of Medical Sciences (RIMS) teaching hospital -Raichur, which will help us to use the medicines rationally and decrease the adverse effects in surgical patients. Methods:A retrospective study was done on post-operative patients of surgery ward in RIMS teaching hospital -Raichur. A total of 574 patients prescriptions/case record forms were collected over a period of 15 months from January 2015 to March 2016 from the medical record section of the hospital for analysis and rationalization. We analyzed the data using the various drug use indicators given by the WHO. Results:The average number of drugs per encounter was 7.04. Ranitidine, analgesics, antibiotics, and intravenous fluids accounted for majority of the drugs prescribed. Appendicectomy (34.84%) was most commonly performed surgical procedure. Percentage of encounters in which an antibiotic prescribed was 99.8%. Percentage of encounters with an injection prescribed was 100%. Percentage of drugs prescribed by generic name was 43.93%. Percentage of drugs prescribed from National List of Essential Medicines 2015 was 99.3%. Conclusion:Our study gave us an in general pattern about the use of drugs in post-operative patients in the surgical ward of a tertiary care hospital. Widespread polypharmacy, particularly in case of the antibiotics, lack of generic prescribing are some concerns that need to be addressed to conform to rational drug therapy. However, prescribing according to the national essential list of medicines is good in our study.

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“…Nutritional supplements and nutraceuticals prescribed were 5.34 %, which was less than as disclosed by Kumar R et al, (10% 5 . Total parenteral fluids prescribed were (9.6%).…”

Section: Introductionmentioning

confidence: 60%

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2022

IJPSR

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Irrational use of medicines is a major problem worldwide. In surgical patients, a greater number of drugs are prescribed So, evaluating prescribing patterns of various medications in surgical inpatients would enable identifying the presence of irrational use, thereby paving a way to rational prescribing. A prospective observational study was conducted in a secondary care hospital for six months. The general surgery, gynecology and orthopedic wards were included in the study. Descriptive statistics were used to assess drug utilization patterns and measure drug use indicators. A total of 97 patients admitted to the orthopedic, general surgery, and gynecology wards were enrolled in the study. The most commonly prescribed medications were Operation theatre (OT) medications, analgesics, Gastrointestinal tract(GIT) related medicines, antimicrobial agents (AMA), and their percentage use was 29.47%, 16.44%, 16.24%, 12.03%, respectively. Based on WHO core prescribing indicators, the average number of drugs per encounter was 15.4, the drugs prescribed from WHO-EML (World Health Organization-Essential Medicines List) were 29.87%, and the total number of prescriptions with injection was 95.8%. From this study, it was observed that prescription patterns highly deviated from the WHO core prescribing indicators, increasing the overall burden to the patient. Drug Utilization Evaluation (DUE) studies on large populations done in a secondary care setting can help to improve prescribing patterns and enhance the quality of care.

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An in-depth study of drugs prescribing pattern in the Surgery Department of a Tertiary Care Teaching Institute in Northern India

Cited by 7 publications

References 2 publications

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

Drug Utilization Study in Post-Operative Patients in the Surgery Ward of a Tertiary Care Teaching Hospital in South India

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