As a critical component of rotating machinery, the health status of bearings is of great significance to ensure the safety of machine operation. Since the vibration signals are interfered by noise during the machine operation, the traditional bearing fault diagnosis model has insufficient feature extraction ability, low diagnostic accuracy, and slow convergence speed. An intelligent bearing fault diagnosis method is proposed based on improved complete ensemble empirical mode decomposition with adaptive noise (ICEEMDAN) and inverted residual convolution neural network integrated with Ghost module (Ghost-IRCNN). Firstly, ICEEMDAN is used to decompose the signals, and the kurtosis-correlation coefficient-margin factor index is proposed to filter and reconstruct the important modal components. Then, the multi-scale sample entropy is used to construct the feature vectors. Finally, the Ghost module, convolution block attention module, and inverted residual bottleneck are combined to build Ghost-IRCNN to realize bearing fault classification and diagnosis. The experimental results show that the proposed method can extract bearing fault features effectively, and the diagnosis accuracy can reach more than 98.80% under complex conditions.