An immunostimulatory polysaccharide (SCP-IIa) from the fruit of Schisandra chinensis (Turcz.) Baill

Lactobacillus sakei K040706 evokes immunostimulatory effects on macrophages through TLR 2-mediated activation

“…In our model, cyclophosphamide reduced thymus and spleen indices, which are important intuitive indices of nonspecific immunity [39]. Several authors have reported that immunostimulating agents could increase thymus and spleen weight in cyclophosphamide-induced immunosuppressed animals [40][41][42].…”

Immunostimulatory polysaccharide isolated from the leaves of Diospyros kaki Thumb modulate macrophage via TLR2

“…Cyclophosphamide was used as the immunosuppressant because it inhibits humoral [50], and cell-mediated immune responses [51]. In our model, the immunosuppressive effect of cyclophosphamide was demonstrated by reduced thymus, spleen, and neutrophil indices, which are important and intuitive indices of nonspecific immunity [52]. Several studies have reported that immunostimulators can increase thymus and spleen weight in cyclophosphamide immunosuppressed animals [53].…”

Immunomodulatory effect of a formula developed from American ginseng and Chinese jujube extracts in mice

“…When mice are immunized with SRBC, Blymphocytes would secrete hemolysin, whose content in serum is used to evaluate the functional status of humoral immunity . T-lymphocytes could eliminate the target cells directly as well as release various cytokines, and their proliferation is crucial for the activation cascade of both humoral and cellular immune responses (Chen et al, 2012). In the present study, serum hemolysin formation and T-lymphocyte proliferation with its mitogen ConA were determined to elucidate the effect of SZC on adaptive immunity.…”