An <i>in vitro</i> study of the action of immune bodies called forth in the blood of rabbits by the injection of the flagellate protozoon <i>Bodo caudatus</i>

Robertson, Muriel

doi:10.1002/path.1700380309

Cited by 3 publications

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“…By feeding it on a pure bacterial culture she was able, in animal immunization experiments, to easily distinguish between antibacterial and anti- Bodo antibodies, and to remove the antibacterial antibodies. She identified two types of specific antibody that would lyse B. caudatus in a complement-dependent manner: a low-titre antibody from non-immunized animals and a high-titre antibody from immunized animals (Robertson, 1934). She also showed a similar phenomenon with ciliates from the Glaucoma-Colpidium group, and that the ciliates could secrete an enveloping sheath to protect themselves and to escape from the low-titre antibodies (Robertson, 1939 b ).…”

Section: Introductionmentioning

confidence: 99%

The remarkable Dr Robertson

Hammarton

2016

Parasitology

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S U M M A R YMuriel Robertson (1883Robertson ( -1973 was a pioneering protozoologist who made a staggering number of important contributions to the fields of parasitology, bacteriology and immunology during her career, which spanned nearly 60 years. These contributions were all the more remarkable given the scientific and social times in which she worked. While Muriel is perhaps best known for her work on the life cycle and transmission of the African trypanosome, Trypanosoma brucei, which she carried out in Uganda at the height of a major Sleeping Sickness epidemic, her work on the Clostridia during the First and Second World Wars made significant contributions to the understanding of anaerobes and to the development of anti-toxoid vaccines, and her work on the immunology of Trichomonas foetus infections in cattle, carried out in collaboration with the veterinarian W. R. Kerr, resulted in changes in farming practices that very quickly eradicated trichomoniasis from cattle herds in Northern Ireland. The significance of her work was recognized with the award of Fellow of the Royal Society in 1947 and an Honorary Doctorate of Law from the University of Glasgow, where she had earlier studied, in 1948.

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Section: Introductionmentioning

confidence: 99%