An <i>Ex Vivo</i> Phantom Validation Study of an MRI-Transrectal Ultrasound Fusion Device for Targeted Prostate Biopsy

Wegelin, O.; Henken, Kirsten; Somford, Diederik M.; Breuking, F. A.; Bosch, Ruud; Swol, Christiaan F. P. van; Melick, Harm H.E. van

doi:10.1089/end.2015.0864

Cited by 9 publications

(4 citation statements)

References 27 publications

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“…Seifabadi et al evaluated the prostate biopsy needle placement accuracy of an MRI-guided robot and found overall system error in phantoms to be 2.5 mm [ 25 ]. Wegelin et al assessed the ex vivo accuracy of an MRI-TRUS fusion guidance device and found the mean overall error in the transverse plane to be 2.33 mm [ 26 ]. In a different study of a 3D ultrasound-guided transrectal biopsy system, the mean needle-segment-to-target distance was 3.6 ± 4.0 mm and mean needle-to-target distance was 3.2 ± 2.4 mm [ 27 ].…”

Section: Conclusion and Discussionmentioning

confidence: 99%

Initial phantom studies for an office-based low-field MR system for prostate biopsy

et al. 2021

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Purpose Prostate cancer is the second most prevalent cancer in US men, with about 192,000 new cases and 33,000 deaths predicted for 2020. With only a 31% 5-year survival rate for patients with an initial diagnosis of stage-four prostate cancer, the necessity for early screening and diagnosis is clear. In this paper, we present navigation accuracy results for Promaxo’s MR system intended to be used in a physician’s office for image-guided transperineal prostate biopsy. Methods The office-based low-field MR system was used to acquire images of prostate phantoms with needles inserted through a transperineal template. Coordinates of the estimated sample core locations in the office-based MR system were compared to ground truth needle coordinates identified in a 1.5T external reference scan. The error was measured as the distance between the planned target and the ground truth core center and as the shortest perpendicular distance between the planned target and the ground truth trajectory of the whole core. Results The average error between the planned target and the ground truth core center was 2.57 ± 1.02 mm, [1.93–3.21] 95% CI. The average error between the planned target to the actual core segment was 2.05 ± 1.24 mm, [1.53–2.56] 95% CI. Conclusion The average navigation errors were below the clinically significant threshold of 5 mm. The initial phantom results demonstrate the feasibility of the office-based system for prostate biopsy.

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Section: Conclusion and Discussionmentioning

confidence: 99%

Initial phantom studies for an office-based low-field MR system for prostate biopsy

et al. 2021

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“…Несмотря на преимущества, МРТ имеет ограничения в применении в клинической практике. Например, при небольших опухолях, которые трудно визуализировать и технически сложно пунктировать, возможность успешного нацеливания на фокус диаметром 2 мм с использованием таргетной биопсии составляет менее 26 % [30,31]. Кроме этого, в исследовании показано, что при оценке поражений для биопсии или хирургического планирования мпМРТ часто недооценивает размер поражения в среднем на 11 мм в диаметре и общий объем в 3 раза [32].…”

Section: клиническое применение таргетной биопсииunclassified

Modern aspects of targeted prostate biopsy

Popov

Орлов

Malevich³

et al. 2021

Onkourologiâ

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Prostate cancer (PCa) is in second place in oncological morbidity in males and is the fifth leading cause of death among the world's population. According to current world statistics, over the past 20 years there has been an increase in primary morbidity, as well as mortality from PCa. The key to diagnosing PCa is a prostate biopsy. Nevertheless, a systemic biopsy under transrectal ultrasound control is the subject of discussion and debate in oncourology, as it has significant drawbacks that affect the qualitative result of the diagnosis of PCa. Given the importance of adequate and staged PCa, various methods of targeted biopsy under magnetic resonance control have been proposed.This review will examine the main features and significance of targeted prostate biopsy, as well as the role of magnetic resonance imaging in the early diagnosis of PCa. The method of targeted biopsy of the prostate gland can improve the detection of PCa in relation to clinically significant forms. In addition, this method is extremely promising and requires further study to further improve the quality of early diagnosis of PCa, especially when selecting patients for radical surgical treatment.

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“…Additional factors important to confluent ablation zone include imaging co-registration error intrinsic in translation of MRI to TRUS (the imaging modality utilized for the majority of focal ablation technologies). Several studies have demonstrated that registration error between MRI and TRUS vary by size of the region of interest as well as registration technique, with elastic registration commonly improving this error ( 33 , 34 ). Treatment planning must also account for alterations in treatment anatomy secondary to treatment such as gland distortion from needle placement or energy absorption and patient movement during treatment ( 35 ).…”

Section: Ensuring Accurate Ablation—defining and Destroying The Indexmentioning

confidence: 99%

Optimizing patient selection for focal therapy—mapping and ablating the index lesion

Wysock¹,

Lepor²

2018

Transl. Androl. Urol.

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An Ex Vivo Phantom Validation Study of an MRI-Transrectal Ultrasound Fusion Device for Targeted Prostate Biopsy

Abstract: MRI-TRUS fusion allows for accurate sampling of MRI-identified lesions with an OE of 2.33 mm. Lesions with a diameter of 3 mm or more can be accurately targeted. These results should be considered the lower limit of in vivo accuracy.

Cited by 9 publications

References 27 publications

Initial phantom studies for an office-based low-field MR system for prostate biopsy

Initial phantom studies for an office-based low-field MR system for prostate biopsy

Modern aspects of targeted prostate biopsy

Optimizing patient selection for focal therapy—mapping and ablating the index lesion

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