An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model
Alejandra Gonzalez Calle,
Javad Paknahad,
Dimitrios Pollalis
et al.
Abstract:Retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are characterized by unrelenting neuronal death. However, electrical stimulation has been shown to induce neuroprotective changes in the retina capable of slowing down the progression of retinal blindness. In this work, a multi-scale computational model and modeling platform were used to design electrical stimulation strategies to better target the bipolar cells (BCs), that along with photoreceptors are affected at th… Show more
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